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(Q21106782)
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English
Enhancer of mRNA decapping 4
mammalian protein found in Homo sapiens
Hedls
enhancer of mRNA-decapping protein 4
EDC4
human enhancer of decapping large subunit
autoantigen Ge-1
autoantigen RCD-8
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6P2E9
part of
WD40/YVTN repeat-like-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q6P2E9
WD40-repeat-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q6P2E9
Enhancer of mRNA-decapping protein 4, WD40 repeat region, protein family
1 reference
based on heuristic
inferred from protein domain or family
WD40 repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6P2E9
encoded by
EDC4
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6P2E9
molecular function
protein binding
determination method
IPI
11 references
retrieved
8 April 2019
stated in
The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
A human microprotein that interacts with the mRNA decapping complex
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
EDC4 interacts with and regulates the dephospho-CoA kinase activity of CoA synthase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
A protein interaction framework for human mRNA degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
retrieved
8 April 2019
stated in
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IPI
cell component
cytoplasm
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
Cytoplasmic detection of a novel protein containing a nuclear localization sequence by human autoantibodies
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IEA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
TAS
P-body
determination method
IDA
IEA
2 references
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2E9&geneProductId=UniProtKB:Q6P2E9
determination method
IEA
retrieved
17 October 2017
stated in
Distinct functions of maternal and somatic Pat1 protein paralogs
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2E9&geneProductId=UniProtKB:Q6P2E9
determination method
IDA
membrane
determination method
IDA
1 reference
retrieved
17 October 2017
stated in
Defining the membrane proteome of NK cells
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2E9&geneProductId=UniProtKB:Q6P2E9
determination method
IDA
nucleus
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IEA
retrieved
8 April 2019
stated in
The immunoreactive region in a novel autoantigen contains a nuclear localization sequence
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IDA
nucleoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IDA
cytoplasmic ribonucleoprotein granule
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IDA
P-body
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IEA
retrieved
8 April 2019
stated in
Distinct functions of maternal and somatic Pat1 protein paralogs
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IBA
membrane
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
Defining the membrane proteome of NK cells
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
HDA
biological process
exonucleolytic catabolism of deadenylated mRNA
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
TAS
deadenylation-independent decapping of nuclear-transcribed mRNA
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
IBA
biological process
determination method
ND
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6P2E9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2E9
determination method
ND
has part(s)
Enhancer of mRNA-decapping protein 4, WD40 repeat region
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q6P2E9
WD40 repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q6P2E9
Identifiers
RefSeq protein ID
NP_055144
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23644
UniProt protein ID
Q6P2E9
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6P2E9
Ensembl protein ID
ENSP00000351811
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000351811
ENSP00000458357
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000458357
ENSP00000459624
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000459624
ENSP00000460563
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000460563
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