(Q21106919)

English

pre-mRNA cleavage required for polyadenylation

The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.

  • GO:0098789
  • pre-mRNA cleavage factor activity

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