(Q21109259)

English

Arrestin beta 1

mammalian protein found in Homo sapiens

ARRB1
non-visual arrestin-2
beta-arrestin-1
Arrestin beta-1
arrestin 2

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49407

Arrestin, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49407

Immunoglobulin E-set

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49407

Arrestin, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49407

Arrestin C-terminal-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Arrestin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Arrestin-like, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

GTPase activator activity

determination method

1 reference

9 May 2019

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

histone acetyltransferase activity

determination method

1 reference

9 May 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

enzyme inhibitor activity

determination method

1 reference

9 May 2019

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

insulin-like growth factor receptor binding

determination method

1 reference

9 May 2019

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

transcription factor binding

determination method

1 reference

9 May 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

mitogen-activated protein kinase kinase binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

clathrin adaptor activity

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

protein phosphorylated amino acid binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

protein binding

determination method

19 references

9 May 2019

Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

The melanosomal/lysosomal protein OA1 has properties of a G protein-coupled receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Ubiquitination of CXCR7 controls receptor trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

β-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

A scanning peptide array approach uncovers association sites within the JNK/beta arrestin signalling complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Role of beta-arrestin 1 in the metastatic progression of colorectal cancer

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

β-Arrestin-1 directly interacts with Gαs and regulates its function

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Functional specialization of beta-arrestin interactions revealed by proteomic analysis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

The EHEC-host interactome reveals novel targets for the translocated intimin receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

AP-2 adaptor complex binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

alpha-1B adrenergic receptor binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

V2 vasopressin receptor binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

phosphoprotein binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

angiotensin receptor binding

determination method

1 reference

9 May 2019

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

ubiquitin protein ligase binding

determination method

1 reference

9 May 2019

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

signaling receptor binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

estrogen receptor binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

alpha-1A adrenergic receptor binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

follicle-stimulating hormone receptor binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

transmembrane transporter binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

clathrin binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

G protein-coupled receptor binding

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

8 April 2019

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

8 April 2019

Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

8 April 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

postsynaptic membrane

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

8 April 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

cell projection

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

dendritic spine

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

heterotrimeric G-protein complex

determination method

1 reference

21 June 2018

Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49407&geneProductId=UniProtKB:P49407

determination method

determination method

1 reference

9 May 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

intracellular anatomical structure

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49407&geneProductId=UniProtKB:P49407

determination method

determination method

1 reference

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

clathrin-coated pit

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

postsynaptic density

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

lysosomal membrane

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

basolateral plasma membrane

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

cytoplasmic vesicle membrane

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

1 reference

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

6 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

plasma membrane

determination method

3 references

9 May 2019

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

cytoplasmic vesicle

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

biological process

positive regulation of Rho protein signal transduction

determination method

1 reference

9 May 2019

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

regulation of G protein-coupled receptor signaling pathway

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of receptor internalization

determination method

1 reference

9 May 2019

Ubiquitination of CXCR7 controls receptor trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

stress fiber assembly

determination method

1 reference

9 May 2019

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

follicle-stimulating hormone signaling pathway

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

platelet activation

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of GTPase activity

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of ERK1 and ERK2 cascade

determination method

positive regulation of insulin secretion involved in cellular response to glucose stimulus

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method

1 reference

9 May 2019

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

phototransduction

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

regulation of transcription, DNA-templated

determination method

1 reference

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49407&geneProductId=UniProtKB:P49407

determination method

transcription, DNA-templated

determination method

1 reference

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49407&geneProductId=UniProtKB:P49407

determination method

positive regulation of peptidyl-serine phosphorylation

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of interleukin-8 production

determination method

1 reference

9 May 2019

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

protein ubiquitination

determination method

1 reference

9 May 2019

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

protein transport

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of protein phosphorylation

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of smooth muscle cell apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of histone H4 acetylation

determination method

1 reference

9 May 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of protein binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of NF-kappaB transcription factor activity

determination method

1 reference

9 May 2019

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of protein ubiquitination

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

G protein-coupled receptor internalization

determination method

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of interleukin-6 production

determination method

1 reference

9 May 2019

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of histone acetylation

determination method

1 reference

9 May 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of protein ubiquitination

determination method

1 reference

9 May 2019

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of ERK1 and ERK2 cascade

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of signal transduction

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

signal transduction

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of GTPase activity

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

apoptotic process

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

membrane organization

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

regulation of apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of cell population proliferation

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of neuron apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

histone acetylation

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

G protein-coupled receptor internalization

determination method

3 references

9 May 2019

Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

negative regulation of Notch signaling pathway

determination method

3 references

9 May 2019

Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

positive regulation of ERK1 and ERK2 cascade

determination method

3 references

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407

determination method

Arrestin-like, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49407

Arrestin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49407

Arrestin C-terminal-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49407

Identifiers

MeSH descriptor ID

subject named as

beta-Arrestin 1

0 references

D12.644.360.024.098.525.500

0 references

D12.776.157.057.005.525.500

0 references

D12.776.476.024.104.525.500

0 references

D12.776.543.090.525.500

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000353124

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000353124

ENSP00000409581

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000409581

ENSP00000433137

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433137

ENSP00000433171

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433171

ENSP00000434196

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434196

ENSP00000436352

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436352

ENSP00000436530

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436530

0 references

Microsoft Academic ID

0 references

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(11 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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