Wikidata

(Q21109594)

English

Bmi1 polycomb ring finger oncogene

mammalian protein found in Mus musculus

  • polycomb complex protein BMI-1
  • Bmi1
  • B lymphoma Mo-MLV insertion region 1
  • polycomb group RING finger protein 4
  • polycomb group ring finger 4
In more languages

Statements

molecular function
protein binding
determination method
IPI
14 references
retrieved
14 February 2019
stated in
Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
The Bmi-1 oncoprotein interacts with dinG and MPh2: the role of RING finger domains
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
Juxtaposed Polycomb complexes co-regulate vertebral identity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
The Bmi-1 oncoprotein interacts with dinG and MPh2: the role of RING finger domains
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
retrieved
14 February 2019
stated in
Lsh controls Hox gene silencing during development
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IPI
cell component
biological process
negative regulation of transcription by RNA polymerase II
determination method
IDA
IGI
IMP
5 references
retrieved
27 February 2018
stated in
Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25916&geneProductId=UniProtKB:P25916
determination method
IMP
retrieved
27 February 2018
stated in
Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25916&geneProductId=UniProtKB:P25916
determination method
IGI
retrieved
27 February 2018
stated in
Juxtaposed Polycomb complexes co-regulate vertebral identity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25916&geneProductId=UniProtKB:P25916
determination method
IGI
retrieved
27 February 2018
stated in
Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25916&geneProductId=UniProtKB:P25916
determination method
IDA
retrieved
27 February 2018
stated in
MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25916&geneProductId=UniProtKB:P25916
determination method
IDA
negative regulation of transcription by RNA polymerase II
determination method
IBA
IDA
IGI
IMP
6 references
retrieved
14 February 2019
stated in
Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IMP
retrieved
14 February 2019
stated in
Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IGI
retrieved
14 February 2019
stated in
Juxtaposed Polycomb complexes co-regulate vertebral identity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IGI
retrieved
14 February 2019
stated in
Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IDA
retrieved
14 February 2019
stated in
MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25916
determination method
IBA

Identifiers

 
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