(Q21109722)

http://www.ebi.ac.uk/interpro/protein/P49450

Histone H3/CENP-A

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49450

Histone H2A/H2B/H3, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

2 references

1 reference

8 April 2019

Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

10 references

8 April 2019

HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

protein heterodimerization activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IEA

nucleosomal DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

chromosome, centromeric region

IEA

5 references

8 April 2019

Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

5 references

17 October 2017

Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450

17 October 2017

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450

17 October 2017

The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

5 references

8 April 2019

Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

CENP-A containing chromatin assembly

IDA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

establishment of mitotic spindle orientation

TAS

1 reference

8 April 2019

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

protein localization to chromosome, centromeric region

IMP

1 reference

8 April 2019

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

1 reference

8 April 2019

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

sister chromatid cohesion

IDA

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450

1 reference

8 April 2019

The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49450

Identifiers

MeSH descriptor ID

D000076247

subject named as

Centromere Protein A

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1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016