(Q21110131)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

1 reference

27 March 2018

The use of dioxygen by HIF prolyl hydroxylase (PHD1)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

NAS

oxygen sensor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

peptidyl-proline 4-dioxygenase activity

3 references

27 March 2018

A conserved family of prolyl-4-hydroxylases that modify HIF

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

27 March 2018

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

27 March 2018

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

peptidyl-proline 4-dioxygenase activity

EXP

5 references

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

5 June 2018

The use of dioxygen by HIF prolyl hydroxylase (PHD1)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

5 June 2018

A conserved family of prolyl-4-hydroxylases that modify HIF

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

5 June 2018

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

5 June 2018

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

peptidyl-proline 4-dioxygenase activity

EXP

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

The use of dioxygen by HIF prolyl hydroxylase (PHD1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

A conserved family of prolyl-4-hydroxylases that modify HIF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

1 reference

8 April 2019

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

positive regulation of protein catabolic process

1 reference

8 April 2019

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

regulation of neuron apoptotic process

1 reference

8 April 2019

Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

peptidyl-proline hydroxylation to 4-hydroxy-L-proline

IMP

1 reference

27 March 2018

A conserved family of prolyl-4-hydroxylases that modify HIF

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96KS0&geneProductId=UniProtKB:Q96KS0

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

cell redox homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

regulation of cell growth

1 reference

8 April 2019

Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

regulation of transcription from RNA polymerase II promoter in response to hypoxia

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

intracellular estrogen receptor signaling pathway

TAS

1 reference

8 April 2019

Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

peptidyl-proline hydroxylation to 4-hydroxy-L-proline

NAS

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

The use of dioxygen by HIF prolyl hydroxylase (PHD1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

8 April 2019

A conserved family of prolyl-4-hydroxylases that modify HIF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96KS0

Oxoglutarate/iron-dependent dioxygenase

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96KS0

Prolyl 4-hydroxylase, alpha subunit

1 reference

stated in

InterPro Release 71.0