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The use of dioxygen by HIF prolyl hydroxylase (PHD1)
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title
The use of dioxygen by HIF prolyl hydroxylase (PHD1)
(English)
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main subject
Egl-9 family hypoxia inducible factor 2
1 reference
stated in
GOA release 2020-03-11
peptidyl-proline 4-dioxygenase activity
1 reference
stated in
GOA release 2020-03-11
author
Christopher J. Schofield
series ordinal
9
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Louise E Horsfall
object named as
Louise E Horsfall
series ordinal
4
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Jonathan M. Gleadle
object named as
Jonathan M Gleadle
series ordinal
3
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Neil J Oldham
object named as
Neil J Oldham
series ordinal
5
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Peter J. Ratcliffe
object named as
Peter J Ratcliffe
series ordinal
8
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Kirsty S Hewitson
series ordinal
2
object named as
Kirsty S Hewitson
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Luke A McNeill
series ordinal
1
object named as
Luke A McNeill
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Christopher J A Pugh
series ordinal
7
object named as
Christopher W Pugh
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Patrick H. Maxwell
series ordinal
6
object named as
Patrick H Maxwell
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language of work or name
English
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publication date
17 June 2002
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published in
Bioorganic & Medicinal Chemistry Letters
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volume
12
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page(s)
1547-50
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issue
12
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cites work
Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of hypoxia-inducible factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the HIF pathway in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PAS superfamily: sensors of environmental and developmental signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
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Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Collagens and collagen-related diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conserved family of prolyl-4-hydroxylases that modify HIF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization and comparative analysis of the EGLN gene family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutagenesis studies on the iron binding ligands of clavaminic acid synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Site-directed mutagenesis and biochemical analysis of the endogenous ligands in the ferrous active site of clavaminate synthase. The His-3 variant of the 2-His-1-carboxylate model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on the active site of deacetoxycephalosporin C synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and mechanism of anthocyanidin synthase from Arabidopsis thaliana
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900219-6
retrieved
7 January 2021
based on heuristic
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Identifiers
DOI
10.1016/S0960-894X(02)00219-6
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PubMed ID
12039559
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ResearchGate publication ID
11332679
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