Wikidata

(Q21110955)

English

TNF receptor superfamily member 1A

mammalian protein found in Homo sapiens

  • TNF-R1
  • tumor necrosis factor receptor superfamily member 1A
  • Tumor necrosis factor receptor type I
  • tumor necrosis factor binding protein 1
  • p60
  • TNFR-I
  • tumor necrosis factor receptor type 1
  • p55
  • tumor necrosis factor receptor 1A isoform beta
  • TNF-RI
  • TNFRSF1A
  • tumor necrosis factor-alpha receptor
  • Tumor necrosis factor receptor 1
  • Receptors, Tumor Necrosis Factor, Type I
In more languages

Statements

molecular function
protein binding
determination method
IPI
29 references
retrieved
8 April 2019
stated in
A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway
GOA
curator
UniProt
UniProt protein ID
P19438
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Effect of antibodies to rat and human cerebral cortex and white matter on heterologous T- and B-cells
GOA
curator
UniProt
UniProt protein ID
P19438
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD
GOA
curator
UniProt
UniProt protein ID
P19438
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
A novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosis
GOA
curator
UniProt
UniProt protein ID
P19438
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
SH3RF2 functions as an oncogene by mediating PAK4 protein stability
GOA
curator
UniProt
UniProt protein ID
P19438
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
RAIDD is a new 'death' adaptor molecule
GOA
curator
UniProt
UniProt protein ID
P19438
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase
GOA
curator
UniProt
UniProt protein ID
P19438
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation
GOA
curator
UniProt
UniProt protein ID
P19438
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Riboflavin kinase couples TNF receptor 1 to NADPH oxidase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
The seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
retrieved
8 April 2019
stated in
Human tumor necrosis factor-alpha receptor. Purification by immunoaffinity chromatography and initial characterization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438
determination method
IPI
cell component
biological process

Identifiers

MeSH descriptor ID
D047888
subject named as
Receptors, Tumor Necrosis Factor, Type I
0 references
Freebase ID
/m/03m3x7b
0 references
Microsoft Academic ID
2779708716
0 references
2910349124
0 references
 
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