Wikidata

(Q21111704)

English

Baculoviral IAP repeat containing 2

mammalian protein found in Homo sapiens

  • BIRC2
  • RING-type E3 ubiquitin transferase BIRC2
  • hIAP2
  • C-IAP1
  • inhibitor of apoptosis protein 2
  • cellular inhibitor of apoptosis 1
  • baculoviral IAP repeat-containing protein 2
  • TNFR2-TRAF-signaling complex protein 2
  • IAP-2
  • RING finger protein 48
  • hIAP-2
  • NFR2-TRAF signalling complex protein
  • IAP homolog B
  • apoptosis inhibitor 1
  • Cellular Inhibitor of Apoptosis Protein 1
  • CIAP1
In more languages

Statements

molecular function
protein binding
determination method
IPI
22 references
retrieved
9 May 2019
stated in
Asymmetric recruitment of cIAPs by TRAF2
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
cIAP1 Localizes to the nuclear compartment and modulates the cell cycle
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Middle domain of human Hsp90 isoforms differentially binds Aha1 in human cells and alters Hsp90 activity in yeast
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Network organization of the human autophagy system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
OTUB1 modulates c-IAP1 stability to regulate signalling pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
retrieved
9 May 2019
stated in
A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IPI
cell component
nucleus
determination method
IBA
IDA
IEA
6 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IEA
retrieved
9 May 2019
stated in
Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IDA
retrieved
9 May 2019
stated in
cIAP1 Localizes to the nuclear compartment and modulates the cell cycle
GOA
curator
UniProt
UniProt protein ID
Q13490
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IDA
retrieved
9 May 2019
stated in
The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
determination method
IBA
biological process

Identifiers

PDB structure ID
 
edit
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q21111704&oldid=2022946627"