(Q24301502)

X-linked inhibitor of apoptosis

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Baculoviral IAP repeat containing 3

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regulation of nucleotide-binding oligomerization domain containing signaling pathway

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Current Opinion in Cell Biology

Pascal Meier

2

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author name string

Juanita Lopez

series ordinal

1

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language of work or name

English

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publication date

December 2010

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published in

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volume

22

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issue

6

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page(s)

872-81

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cites work

Downregulation of XIAP expression in ovarian cancer cells induces cell death in vitro and in vivo.

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

The inhibitors of apoptosis (IAPs) as cancer targets

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7 January 2021

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

TNF-alpha induces two distinct caspase-8 activation pathways

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Necroptosis: a specialized pathway of programmed necrosis

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Pattern recognition receptors and inflammation

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Immunity, Inflammation, and Cancer

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Nonresolving inflammation

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Asymmetric recruitment of cIAPs by TRAF2

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Lucifer's labyrinth--ten years of path finding in cell death

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

A tangled web of ubiquitin chains: breaking news in TNF-R1 signaling.

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Ubiquitin-mediated regulation of apoptosis

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https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Nuclear factor-kappaB in cancer development and progression

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Cancer-related inflammation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Ubiquitylation in innate and adaptive immunity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Identification of RIP1 kinase as a specific cellular target of necrostatins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Integrating cell-signalling pathways with NF-kappaB and IKK function

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

IAP-targeted therapies for cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

A ubiquitin ligase complex assembles linear polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

An RNA interference screen identifies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

The emerging complexity of protein ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

XIAP mediates NOD signaling via interaction with RIP2

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Constitutive activation of nuclear factor-kappaB is preferentially involved in the proliferation of basal-like subtype breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Regulation and function of NF-kappaB transcription factors in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

NOD-like receptors: role in innate immunity and inflammatory disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

XIAP regulates cytosol-specific innate immunity to Listeria infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRs

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021

Constitutive non-canonical NFkappaB signaling in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CEB.2010.08.025

7 January 2021