(Q48548442)

12 February 2018

title

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo (English)

1 reference

12 February 2018

0 references

1

1 reference

12 February 2018

Klaus-Michael Debatin

series ordinal

4

1 reference

12 February 2018

Michael Weller

series ordinal

3

object named as

Michael Weller

1 reference

12 February 2018

2

Wolfgang Wick

1 reference

12 February 2018

language of work or name

English

0 references

publication date

15 July 2002

1 reference

12 February 2018

published in

Nature Medicine

1 reference

12 February 2018

volume

8

1 reference

12 February 2018

issue

8

1 reference

12 February 2018

page(s)

808-815

1 reference

12 February 2018

Cancer epidemiology in the last century and the next decade

cites work

1 reference

7 January 2021

1 reference

7 January 2021

1 reference

7 January 2021

From bench to clinic with apoptosis-based therapeutic agents

1 reference

7 January 2021

The biochemistry of apoptosis

1 reference

7 January 2021

Cellular stress response and apoptosis in cancer therapy.

1 reference

7 January 2021

Apoptosis and the response to anticancer therapy.

1 reference

7 January 2021

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

1 reference

7 January 2021

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

1 reference

7 January 2021

Death receptors: signaling and modulation

1 reference

7 January 2021

The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

1 reference

7 January 2021

Caspases: enemies within

1 reference

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

7 January 2021

Mitochondrial control of cell death

1 reference

7 January 2021

Cross-talk in cell death signaling

1 reference

7 January 2021

The Bcl-2 protein family

1 reference

7 January 2021

Cell death inhibition: keeping caspases in check

1 reference

7 January 2021

IAP family proteins--suppressors of apoptosis

1 reference

7 January 2021

Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma

1 reference

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

7 January 2021

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

7 January 2021

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 reference

7 January 2021

Apoptotic pathways: paper wraps stone blunts scissors

1 reference

7 January 2021

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

1 reference

7 January 2021

Structural basis of IAP recognition by Smac/DIABLO

1 reference

7 January 2021

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

1 reference

7 January 2021

MHC haplotype-dependent regulation of MOG-induced EAE in rats.

1 reference

7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

7 January 2021

Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4

1 reference

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

7 January 2021

The potential of TRAIL for cancer chemotherapy

1 reference

7 January 2021

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

1 reference

7 January 2021

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

1 reference

7 January 2021

Role of BAX in the apoptotic response to anticancer agents

1 reference

7 January 2021

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

1 reference

7 January 2021

1 reference

7 January 2021

TRAIL/Apo-2-ligand-induced apoptosis in human T cells.

1 reference

7 January 2021

Improved culture methods to expand Schwann cells with altered growth behaviour from CMT1A patients

1 reference

7 January 2021

Cell-penetrating peptides.

1 reference

7 January 2021

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM735

1 reference

12 February 2018

1 reference

12 February 2018