(Q43583436)

24 November 2017

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis (English)

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24 November 2017

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1

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24 November 2017

Klaus-Michael Debatin

series ordinal

6

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24 November 2017

5

Kroemer G

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24 November 2017

4

Susin SA

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24 November 2017

Meyer E

2

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24 November 2017

Friesen C

series ordinal

3

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24 November 2017

language of work or name

English

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publication date

1 March 2001

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24 November 2017

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24 November 2017

20

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24 November 2017

1063-1075

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24 November 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204141

24 November 2017

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cites work

Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Caspases induce cytochrome c release from mitochondria by activating cytosolic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Cytotoxic Drugs, Programmed Cell Death, and the Immune System: Defining New Roles in an Old Play

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Induction of CD95 ligand and apoptosis by doxorubicin is modulated by the redox state in chemosensitive- and drug-resistant tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Death ligand/receptor-independent caspase activation mediates drug-induced cytotoxic cell death in human malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Differential requirement for caspase 9 in apoptotic pathways in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Thymineless death in colon carcinoma cells is mediated via fas signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Induction of apoptosis by cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Mitochondrial control of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

The proto-oncogene Bcl-2 and its role in regulating apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the Fas (APO-1/CD95) receptor/ligand system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Mitochondrial release of caspase-2 and -9 during the apoptotic process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

Chemosensitivity of solid tumor cellsin vitro is related to activation of the CD95 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

inferred from DOI database lookup

7 January 2021

based on heuristic

Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

inferred from DOI database lookup

7 January 2021

based on heuristic

Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204141

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1204141

1 reference

Dimensions Publication ID

24 November 2017

0 references

1 reference