(Q24300707)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18022362%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis (English)

1 reference

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26 December 2019

0 references

1 reference

2

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26 December 2019

author name string

Eugene Varfolomeev

1

1 reference

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26 December 2019

Sarah M Wayson

3

1 reference

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26 December 2019

Anna V Fedorova

4

1 reference

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26 December 2019

Nobuhiko Kayagaki

5

1 reference

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26 December 2019

Parie Garg

6

1 reference

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26 December 2019

Kerry Zobel

7

1 reference

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26 December 2019

Jasmin N Dynek

8

1 reference

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26 December 2019

Linda O Elliott

9

1 reference

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26 December 2019

Heidi J A Wallweber

10

1 reference

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26 December 2019

John A Flygare

11

1 reference

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26 December 2019

Wayne J Fairbrother

12

1 reference

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26 December 2019

Kurt Deshayes

13

1 reference

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26 December 2019

Vishva M Dixit

14

1 reference

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26 December 2019

Domagoj Vucic

15

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26 December 2019

language of work or name

English

0 references

publication date

1 November 2007

1 reference

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26 December 2019

number of pages

13

1 reference

inferred from page(s)

published in

Cell

1 reference

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26 December 2019

volume

131

1 reference

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26 December 2019

issue

4

1 reference

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26 December 2019

page(s)

669-681

1 reference

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The inhibitors of apoptosis (IAPs) as cancer targets

26 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Development of Peptidomimetics Targeting IAPs

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

57 Dye uptake method for assay of interferon activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Apoptosis control by death and decoy receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

An exegesis of IAPs: salvation and surprises from BIR motifs

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

The CARD domain: a new apoptotic signalling motif

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Apoptosis-targeted therapies for cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Donor-acceptor (electronic) coupling in the precursor complex to organic electron transfer: intermolecular and intramolecular self-exchange between phenothiazine redox centers

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Structure-based design of potent, conformationally constrained Smac mimetics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Structural basis of IAP recognition by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Ubiquitin signalling in the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Clonogenic assay of cells in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

IAPs, RINGs and ubiquitylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

IAP proteins: blocking the road to death's door

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Alterations in the apoptotic machinery and their potential role in anticancer drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

The inhibitors of apoptosis: there is more to life than Bcl2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Signaling to NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

TNF-R1 signaling: a beautiful pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Mechanisms and genes of cellular suicide

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

Biochemical pathways of caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.10.030

7 January 2021

10.1016/J.CELL.2007.10.030

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18022362%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017