(Q35567264)

8 August 2017

1 reference

title

Alterations in the apoptotic machinery and their potential role in anticancer drug resistance (English)

1 reference

antineoplastic resistance

8 August 2017

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576849

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

24 March 2024

David L Vaux

2

0 references

Scott H Kaufmann

object named as

Scott H Kaufmann

1

0 references

language of work or name

English

0 references

publication date

1 October 2003

1 reference

8 August 2017

20 October 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576849

full work available at URL

24 March 2024

https://www.nature.com/articles/1206945.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576849

https://www.nature.com/articles/1206945.pdf

24 March 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

https://www.nature.com/articles/1206945

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

24 March 2024

1 reference

8 August 2017

22

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8 August 2017

7414-7430

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8 August 2017

47

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206945

8 August 2017

0 references

cites work

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Biochemical pathways of caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Quantitatively determined survivin expression levels are of prognostic value in human gliomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The role of the Bcl-2 protein family in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Proliferation, cell cycle and apoptosis in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Does cancer therapy trigger cell suicide?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

A matter of life and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Cell cycle control and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The biochemistry of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Cellular stress response and apoptosis in cancer therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

BH3-Only proteins-essential initiators of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Molecular cloning and functional analysis of the murine bax gene promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Chemosensitisation of malignant melanoma by BCL2 antisense therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Livin, a novel inhibitor of apoptosis protein family member

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Induction of apoptosis by cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Apoptosis in cancer: cause and cure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The MRP family of drug efflux pumps

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: a translational perspective.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Clinical applications of TNF-alpha in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Apoptotic Cell Death During Treatment of Leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Destabilizing influences in apoptosis: sowing the seeds of IAP destruction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

NADH oxidase activity of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Overexpression of the Bcl-2 protein increases the half-life of p21Bax

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Apoptosis and the response to anticancer therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Mitochondria: releasing power for life and unleashing the machineries of death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Apoptosis. Life and death decisions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Inactivating mutations of the caspase-10 gene in gastric cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Caspase-2 can trigger cytochrome C release and apoptosis from the nucleus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Dimer formation drives the activation of the cell death protease caspase 9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Cell death regulation by the mammalian IAP antagonist Diablo/Smac.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Role of BAX in the apoptotic response to anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Divinations and surprises: genetic analysis of caspase function in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206945

7 January 2021

Cell cycle checkpoint signaling through the ATM and ATR kinases

1

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Life-or-death decisions by the Bcl-2 protein family.

24 March 2024

3

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Chromosomal passengers and the (aurora) ABCs of mitosis

24 March 2024

5

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

24 March 2024

6

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Involvement of the hepatocyte growth factor/scatter factor receptor c-met and of Bcl-xL in the resistance of oropharyngeal cancer to ionizing radiation.

24 March 2024

7

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

24 March 2024

9

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Apoptosis: Mechanisms and Roles in Pathology

24 March 2024

10

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

24 March 2024

12

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Defects in regulation of apoptosis in caspase-2-deficient mice

24 March 2024

18

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

A unified model for apical caspase activation

24 March 2024

20

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Expression and prognostic significance of Bcl-2 family proteins in myelodysplastic syndromes

24 March 2024

21

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

24 March 2024

23

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

24 March 2024

34

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis

24 March 2024

39

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR–ABL tyrosine kinase, CGP 57148

24 March 2024

44

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis

24 March 2024

45

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

24 March 2024

46

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

IAP family proteins--suppressors of apoptosis

24 March 2024

47

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

24 March 2024

49

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors

24 March 2024

51

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis

24 March 2024

55

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

24 March 2024

63

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

The complexity of p53 modulation: emerging patterns from divergent signals

24 March 2024

64

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

24 March 2024

Cancer statistics, 2001

67

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

BCL-2 family members and the mitochondria in apoptosis

24 March 2024

69

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Characterization of XIAP-deficient mice

24 March 2024

76

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Understanding IAP function and regulation: a view from Drosophila

24 March 2024

80

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Adult Apaf-1-deficient mice exhibit male infertility

24 March 2024

86

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Apoptosis and drug response

24 March 2024

88

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

24 March 2024

91

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor.

24 March 2024

95

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

24 March 2024

98

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Aberrant expression of caspase cascade regulatory genes in adult T-cell leukaemia: survivin is an important determinant for prognosis

24 March 2024

99

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Emerging information on the use of rituximab in chronic lymphocytic leukemia

24 March 2024

106

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Advances in classification and therapy of indolent B-cell malignancies

24 March 2024

107

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells

24 March 2024

114

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

24 March 2024

124

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Overexpression of Bcl-x(L) promotes chemotherapy resistance of mammary tumors in a syngeneic mouse model

24 March 2024

126

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

24 March 2024

Cancer therapy and p53.

129

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Biochemical modulation of tumor cell energy in vivo: II. A lower dose of adriamycin is required and a greater antitumor activity is induced when cellular energy is depressed.

24 March 2024

132

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Genetics of programmed cell death in C. elegans: past, present and future.

24 March 2024

139

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf.

24 March 2024

148

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Cell death control in lymphocytes.

24 March 2024

151

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Caspase structure, proteolytic substrates, and function during apoptotic cell death

24 March 2024

152

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

24 March 2024

154

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Generation and characterization of Smac/DIABLO-deficient mice.

24 March 2024

156

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

24 March 2024

162

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

24 March 2024

163

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.

24 March 2024

166

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Dysregulation of apoptosis in cancer

24 March 2024

168

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer.

24 March 2024

173

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

24 March 2024

174

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

IAP proteins: blocking the road to death's door

24 March 2024

175

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Bcl-2 mediates chemoresistance in matched pairs of primary E(mu)-myc lymphomas in vivo

24 March 2024

176

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Apoptosis signaling by death receptors.

24 March 2024

177

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Differential inactivation of caspase-8 in lung cancers.

24 March 2024

184

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

24 March 2024

191

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Tumor necrosis factor induces tumor necrosis via tumor necrosis factor receptor type 1-expressing endothelial cells of the tumor vasculature

24 March 2024

195

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?

24 March 2024

196

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

24 March 2024

199

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

24 March 2024

204

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

24 March 2024

210

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

24 March 2024

212

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

24 March 2024

220

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Discerning malignancy in adrenocortical tumors: are molecular markers useful?

24 March 2024

221

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

24 March 2024

223

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Cell-cycle arrest versus cell death in cancer therapy

24 March 2024

224

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides

24 March 2024

228

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

24 March 2024

233

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

PUMA induces the rapid apoptosis of colorectal cancer cells

24 March 2024

236

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Caspase knockouts: matters of life and death.

24 March 2024

239

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

The machinery of programmed cell death.

24 March 2024

242

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

24 March 2024

243

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206945

24 March 2024

Identifiers

1 reference

Dimensions Publication ID

8 August 2017

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