(Q35567296)

8 August 2017

1 reference

title

The MRP family of drug efflux pumps (English)

1 reference

antineoplastic resistance

8 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576857

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

24 March 2024

author name string

Gary D. Kruh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576857

24 March 2024

Martin G. Belinsky

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576857

24 March 2024

language of work or name

English

0 references

publication date

1 October 2003

1 reference

8 August 2017

20 October 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576857

full work available at URL

24 March 2024

https://www.nature.com/articles/1206953.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576857

https://www.nature.com/articles/1206953.pdf

24 March 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

https://www.nature.com/articles/1206953

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

24 March 2024

1 reference

8 August 2017

22

1 reference

8 August 2017

7537-7552

1 reference

8 August 2017

47

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206953

8 August 2017

0 references

cites work

Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Membrane topology and glycosylation of the human multidrug resistance-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Extracellular cAMP inhibits proximal reabsorption: are plasma membrane cAMP receptors involved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

MRP9, an unusual truncated member of the ABC transporter superfamily, is highly expressed in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Mutations in ABCC6 cause pseudoxanthoma elasticum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Differential Modulation of the Human Liver Conjugate Transporters MRP2 and MRP3 by Bile Acids and Organic Anions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Effects of chronic ethacrynic acid exposure on glutathione conjugation and MRP expression in human colon tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Rhodamine 123 binds to multiple sites in the multidrug resistance protein (MRP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Mrp2-deficiency in the rat impairs biliary and intestinal excretion and influences metabolism and disposition of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Chronic idiopathic jaundice with unidentified pigment in liver cells; a new clinicopathologic entity with a report of 12 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2 (MRP2/MOAT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The multidrug resistance protein MRP1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The ATP-dependent glutathione S-conjugate export pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

cDNA cloning and genomic organization of the murine MRP7, a new ATP-binding cassette transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Binding of a photoaffinity analogue of glutathione to MRP1 (ABCC1) within two cytoplasmic regions (L0 and L1) as well as transmembrane domains 10-11 and 16-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

MRP3, an organic anion transporter able to transport anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

MRP subfamily transporters and resistance to anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Identification of the biosynthetic leukotriene C4 export pump in murine mastocytoma cells as a homolog of the multidrug-resistance protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Role of the Multidrug Resistance Protein 1 in protection from heavy metal oxyanions: investigations in vitro and in MRP1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Adriamycin resistance in HL60 cells in the absence of detectable P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

A PDZ-interacting domain in CFTR is an apical membrane polarization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Structural requirements for the apical sorting of human multidrug resistance protein 2 (ABCC2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Role of multidrug resistance protein 1 (MRP1) and glutathione S-transferase A1-1 in alkylating agent resistance. Kinetics of glutathione conjugate formation and efflux govern differential cellular sensitivity to chlorambucil versus melphalan toxicit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

High Functional P-glycoprotein Activity is More Often Present in T-cell Acute Lymphoblastic Leukaemic Cells in Adults than in Children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Expression and localization of the multidrug resistance-associated protein 3 in rat small and large intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Enhancement of glucuronosyl etoposide transport by glutathione in multidrug resistance-associated protein-overexpressing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Purification and characteristics of recombinant human folylpoly-gamma-glutamate synthetase expressed at high levels in insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Messenger RNA analysis of the multidrug resistance related protein (MRP1) and the lung resistance protein (LRP) in de novo and relapsed childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

MRP6 (ABCC6) detection in normal human tissues and tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Tissue distribution and induction of human multidrug resistant protein 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Isolation of a novel human canalicular multispecific organic anion transporter, cMOAT2/MRP3, and its expression in cisplatin-resistant cancer cells with decreased ATP-dependent drug transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Molecular genetics of pseudoxanthoma elasticum: a metabolic disorder at the environment-genome interface?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Resistance of human multidrug resistance-associated protein 1-overexpressing lung tumor cells to the anticancer drug arsenic trioxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Overexpression of the multidrug resistance-associated protein (MRP1) in human heavy metal-selected tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

Lung resistance-related protein as a predictor of clinical outcome in advanced testicular germ-cell tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

A reciprocal relationship between the genetic diversity at two metabolically-linked isozyme loci in several conifer species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

The multidrug resistance protein is photoaffinity labeled by a quinoline-based drug at multiple sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

Major photoaffinity drug binding sites in multidrug resistance protein 1 (MRP1) are within transmembrane domains 10-11 and 16-17

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

Single amino acid substitution of rat MRP2 results in acquired transport activity for taurocholate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

Expression pattern of MRP in human tissues and adult solid tumor cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

Glutathione-dependent binding of a photoaffinity analog of agosterol A to the C-terminal half of human multidrug resistance protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206953

7 January 2021

MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer

12

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.

24 March 2024

59

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2)

24 March 2024

72

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

Transport function and hepatocellular localization of mrp6 in rat liver

24 March 2024

104

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

Biliary excretion of 17beta-estradiol 17beta-D-glucuronide is predominantly mediated by cMOAT/MRP2

24 March 2024

113

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

Expression of members of the multidrug resistance protein family in human term placenta

24 March 2024

150

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

24 March 2024

169

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206953

24 March 2024

Identifiers

1 reference

8 August 2017

1 reference