(Q34502459)

2 August 2017

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title

MRP subfamily transporters and resistance to anticancer agents (English)

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2 August 2017

Kruh GD

1

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2 August 2017

Zeng H

2

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2 August 2017

Rea PA

3

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2 August 2017

Liu G

4

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2 August 2017

Chen ZS

5

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2 August 2017

Lee K

6

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2 August 2017

Belinsky MG

7

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2 August 2017

publication date

1 December 2001

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Journal of Bioenergetics and Biomembranes

2 August 2017

published in

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2 August 2017

volume

33

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2 August 2017

issue

6

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2 August 2017

page(s)

493-501

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Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter

2 August 2017

cites work

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12 December 2020

Mutations in ABCC6 cause pseudoxanthoma elasticum

1 reference

12 December 2020

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.

1 reference

12 December 2020

Multidrug resistance: molecular mechanisms and clinical relevance

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12 December 2020

pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells

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12 December 2020

A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance

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12 December 2020

Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane

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12 December 2020

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database

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12 December 2020

Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells

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12 December 2020

Transport of amphipathic anions by human multidrug resistance protein 3

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12 December 2020

Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene.

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12 December 2020

Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution

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12 December 2020

Functional Analysis of a Canalicular Multispecific Organic Anion Transporter Cloned from Rat Liver

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12 December 2020

ATP-dependent efflux of 2,4-dinitrophenyl-S-glutathione. Properties of two distinct transport systems in inside-out vesicles from L1210 cells and a variant subline with altered efflux of methotrexate and cholate

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12 December 2020

Expression pattern of MRP in human tissues and adult solid tumor cell lines

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12 December 2020

ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

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12 December 2020

Mechanisms of multidrug resistance in HL60 cells: detection of resistance-associated proteins with antibodies against synthetic peptides that correspond to the deduced sequence of P-glycoprotein.

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12 December 2020

Frequent coordinated overexpression of the MRP/GS-X pump and gamma-glutamylcysteine synthetase genes in human colorectal cancers

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12 December 2020

Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome

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12 December 2020

Role of glutathione and dependent enzymes in anthracycline-resistant HL60/AR cells.

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12 December 2020

A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells

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12 December 2020

ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates

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12 December 2020

MRP3, a new ATP-binding cassette protein localized to the canalicular domain of the hepatocyte

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12 December 2020

Adriamycin resistance in HL60 cells in the absence of detectable P-glycoprotein

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12 December 2020

Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation

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12 December 2020

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells

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12 December 2020

Functional expression of the rat liver canalicular isoform of the multidrug resistance-associated protein

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12 December 2020

Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump

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12 December 2020

Isolation of a novel human canalicular multispecific organic anion transporter, cMOAT2/MRP3, and its expression in cisplatin-resistant cancer cells with decreased ATP-dependent drug transport

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12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

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12 December 2020

Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells

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12 December 2020

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

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12 December 2020

Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells

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12 December 2020

The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein

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12 December 2020

Double knockout of the MRP gene leads to increased drug sensitivity in vitro

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12 December 2020

Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells

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12 December 2020

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

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12 December 2020

Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents.

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12 December 2020

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

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12 December 2020

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

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12 December 2020

Adriamycin resistance in HL60 cells and accompanying modification of a surface membrane protein contained in drug-sensitive cells

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12 December 2020

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells

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12 December 2020

MRP3, an organic anion transporter able to transport anti-cancer drugs

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12 December 2020

Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

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12 December 2020

Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein

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12 December 2020

Biliary excretion of bile acid conjugates in a hyperbilirubinemic mutant sprague-dawley rat

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12 December 2020

Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes

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12 December 2020

MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver

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12 December 2020

Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats.

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12 December 2020

A multidrug resistance transporter from human MCF-7 breast cancer cells

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12 December 2020

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

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12 December 2020

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

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12 December 2020

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

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12 December 2020

Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.

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12 December 2020

Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine

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12 December 2020

Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione

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12 December 2020

Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia

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12 December 2020

cDNA Cloning of a Short Type of Multidrug Resistance Protein Homologue,SMRP,from a Human Lung Cancer Cell Line

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12 December 2020

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines

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12 December 2020

Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells.

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12 December 2020

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

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12 December 2020

Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression

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12 December 2020

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

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12 December 2020

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

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12 December 2020

Comparative evaluation by semiquantitative reverse transcriptase polymerase chain reaction of MDR1, MRP and GSTp gene expression in breast carcinomas

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12 December 2020

Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR.

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12 December 2020

A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation

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12 December 2020

The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides

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12 December 2020

Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats

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12 December 2020

Transport function and hepatocellular localization of mrp6 in rat liver

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12 December 2020

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

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12 December 2020

Mechanisms and interaction of vinblastine and reduced glutathione transport in membrane vesicles by the rabbit multidrug resistance protein Mrp2 expressed in insect cells

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12 December 2020

The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance

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12 December 2020

MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

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12 December 2020

Adenosine triphosphate-dependent transport of anionic conjugates by the rabbit multidrug resistance-associated protein Mrp2 expressed in insect cells.

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12 December 2020

ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

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12 December 2020

Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2)

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12 December 2020

Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump

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12 December 2020

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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12 December 2020

The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line

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12 December 2020

Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells

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12 December 2020

Isolation and characterization of adriamycin-resistant HL-60 cells which are not defective in the initial intracellular accumulation of drug

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12 December 2020

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage

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12 December 2020

Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2.

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12 December 2020

Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum

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12 December 2020

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

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12 December 2020

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance

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12 December 2020

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

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12 December 2020

Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins

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12 December 2020

Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia

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12 December 2020

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

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12 December 2020

Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).

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12 December 2020

Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter

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12 December 2020

Identifiers

DOI

10.1023/A:1012827221844

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Dimensions Publication ID

2 August 2017

1047013523

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