(Q44394457)

English

Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2.

scientific article published on 7 April 2003

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scholarly article

1 reference

Europe PubMed Central

2 December 2017

Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2. (English)

1 reference

Europe PubMed Central

2 December 2017

multiple drug resistance

1 reference

based on heuristic

inferred from title

author name string

Toshikazu Konno

1

1 reference

Europe PubMed Central

2 December 2017

Takuya Ebihara

2

1 reference

Europe PubMed Central

2 December 2017

Keiji Hisaeda

3

1 reference

Europe PubMed Central

2 December 2017

Takeshi Uchiumi

4

1 reference

Europe PubMed Central

2 December 2017

Takanori Nakamura

5

1 reference

Europe PubMed Central

2 December 2017

Takayuki Shirakusa

6

1 reference

Europe PubMed Central

2 December 2017

Michihiko Kuwano

7

1 reference

Europe PubMed Central

2 December 2017

Morimasa Wada

8

1 reference

Europe PubMed Central

2 December 2017

language of work or name

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publication date

7 April 2003

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Europe PubMed Central

2 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

2 December 2017

278

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Europe PubMed Central

2 December 2017

22908-22917

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Europe PubMed Central

2 December 2017

25

1 reference

Europe PubMed Central

2 December 2017

Biology of the multidrug resistance-associated protein, MRP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Structural, mechanistic and clinical aspects of MRP1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2 (MRP2/MOAT).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Structural requirements for the apical sorting of human multidrug resistance protein 2 (ABCC2).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Glycans in post-Golgi apical targeting: sorting signals or structural props?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Rhodamine 123 binds to multiple sites in the multidrug resistance protein (MRP1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302868200

21 January 2018

Identifiers

10.1074/JBC.M302868200

1 reference

Europe PubMed Central

2 December 2017

1 reference

Europe PubMed Central

2 December 2017

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