(Q44108486)

English

Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity

scientific article published on 18 August 2002

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scholarly article

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Europe PubMed Central

29 November 2017

Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity (English)

1 reference

Europe PubMed Central

29 November 2017

transmembrane transport

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transmembrane protein

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multiple drug resistance

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based on heuristic

inferred from title

Susan P.C. Cole

3

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Europe PubMed Central

29 November 2017

2

object named as

Roger G Deeley

1 reference

Europe PubMed Central

29 November 2017

author name string

Anass Haimeur

1

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Europe PubMed Central

29 November 2017

language of work or name

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publication date

18 August 2002

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Europe PubMed Central

29 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

29 November 2017

277

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Europe PubMed Central

29 November 2017

41326-41333

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Europe PubMed Central

29 November 2017

44

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Europe PubMed Central

29 November 2017

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Phenomenology and scientific progress.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

A multidrug resistance transporter from human MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

A family of drug transporters: the multidrug resistance-associated proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Membrane topology of the amino-terminal region of the sulfonylurea receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

MRP3, an organic anion transporter able to transport anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Helical membrane protein folding, stability, and evolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Charged residues in transmembrane domains II and XI of a vesicular monoamine transporter form a charge pair that promotes high affinity substrate recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

A new missense mutation (E92K) in the first transmembrane domain of the CFTR gene causes a benign cystic fibrosis phenotype

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206228200

21 January 2018

Identifiers

10.1074/JBC.M206228200

1 reference

Europe PubMed Central

29 November 2017

1 reference

Europe PubMed Central

29 November 2017

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