(Q63408384)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

review article

1 reference

title

A matter of life and death (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

Gerard I Evan

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

publication date

1 February 2002

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

19-30

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells

10 November 2019

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Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death

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7 January 2021

Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

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7 January 2021

Stress management - heat shock protein-70 and the regulation of apoptosis

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7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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7 January 2021

Biochemical pathways of caspase activation during apoptosis

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7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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7 January 2021

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

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7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

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7 January 2021

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

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7 January 2021

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

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7 January 2021

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

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7 January 2021

A matter of life and cell death

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7 January 2021

Proliferation, cell cycle and apoptosis in cancer

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7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

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7 January 2021

Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts

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7 January 2021

Oncogene-dependent apoptosis is mediated by caspase-9.

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7 January 2021

Antisense therapeutics: lessons from early clinical trials

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7 January 2021

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7 January 2021

Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL+ leukemic cells and induces apoptosis.

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7 January 2021

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

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7 January 2021

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

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7 January 2021

Oncogenes and cell death

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7 January 2021

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

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7 January 2021

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

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7 January 2021

Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

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7 January 2021

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

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7 January 2021

A 'non-canonical' DNA-binding element mediates the response of the Fas-ligand promoter to c-Myc.

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7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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7 January 2021

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

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7 January 2021

NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis

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7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

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7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

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7 January 2021

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

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7 January 2021

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

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7 January 2021

Activation of p53 by oncogenes

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7 January 2021

Genetic analysis of apoptotic and survival signals

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7 January 2021

Breaking the mitochondrial barrier

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7 January 2021

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

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7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

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7 January 2021

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

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7 January 2021

Apaf-1 is a transcriptional target for E2F and p53

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7 January 2021

PUMA, a novel proapoptotic gene, is induced by p53

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7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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7 January 2021

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

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7 January 2021

Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

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7 January 2021

Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

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7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

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7 January 2021

Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

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7 January 2021

Social controls on cell survival and cell death

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7 January 2021

Adenovirus E1A oncogene expression in tumor cells enhances killing by TNF-related apoptosis-inducing ligand (TRAIL).

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7 January 2021

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

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7 January 2021

Role of NF-κB in p53-mediated programmed cell death

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7 January 2021

Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis

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7 January 2021

Dominant negative MYC blocks transformation by ABL oncogenes

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7 January 2021

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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7 January 2021

Death the Fas way: regulation and pathophysiology of CD95 and its ligand

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7 January 2021

The INK4a/ARF network in tumour suppression

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7 January 2021

Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas

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7 January 2021

Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells

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7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

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7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

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7 January 2021

Modulation of cellular apoptotic potential: contributions to oncogenesis

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7 January 2021

Caspase-9 can be activated without proteolytic processing

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7 January 2021

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

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7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

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7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

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7 January 2021

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

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7 January 2021

AKT plays a central role in tumorigenesis

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7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

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7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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7 January 2021

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

1 reference

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7 January 2021

Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.

1 reference

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7 January 2021

Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process

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7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

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7 January 2021

Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity

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7 January 2021

Regulation of p53 function

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7 January 2021

Cell death: the significance of apoptosis

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7 January 2021

PUMA induces the rapid apoptosis of colorectal cancer cells

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7 January 2021

The mitochondrion in apoptosis: how Pandora's box opens

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7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

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7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

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7 January 2021

10.1016/S1535-6108(02)00024-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12086884%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference