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Anoikis mechanisms
scientific article (publication date: October 2001)
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Europe PubMed Central
title
Anoikis mechanisms
(English)
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author name string
S M Frisch
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1
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R A Screaton
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2
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language of work or name
English
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publication date
October 2001
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published in
Current Opinion in Cell Biology
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volume
13
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issue
5
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page(s)
555-62
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cites work
Disruption of epithelial cell-matrix interactions induces apoptosis
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The extracellular matrix as a cell survival factor
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Prolonged cell survival enhances peritoneal dissemination of gastric cancer cells
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Adhesion-mediated signaling in the regulation of mammary epithelial cell survival
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Apoptosis, anoikis and their relevance to the pathobiology of colon cancer
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Comparison of paclitaxel-, 5-fluoro-2'-deoxyuridine-, and epidermal growth factor (EGF)-induced apoptosis. Evidence for EGF-induced anoikis
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beta1 integrin antagonism on adherent, differentiated human neuroblastoma cells triggers an apoptotic signaling pathway
1 reference
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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
1 reference
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Integrin signaling
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Cell adhesion molecules, signal transduction and cell growth
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Cell-substrate interactions and signaling through ILK
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Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells
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Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343
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The integrin-linked kinase (ILK) suppresses anoikis
1 reference
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Crossref
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7 January 2021
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Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex
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7 January 2021
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Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60.
1 reference
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New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway
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Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion
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Transcriptional repression by RB-E2F and regulation of anchorage-independent survival
1 reference
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reference URL
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7 January 2021
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Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling
1 reference
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Crossref
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7 January 2021
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Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival
1 reference
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FAK integrates growth-factor and integrin signals to promote cell migration
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Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.
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Control of adhesion-dependent cell survival by focal adhesion kinase
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Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain
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p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB
1 reference
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7 January 2021
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Cellular survival: a play in three Akts
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7 January 2021
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The Akt proto-oncogene links Ras to Pak and cell survival signals
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7 January 2021
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p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis
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The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis
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Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
1 reference
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MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors
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Bcl-2 targets the protein kinase Raf-1 to mitochondria
1 reference
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7 January 2021
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p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1
1 reference
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Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338
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7 January 2021
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alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase
1 reference
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7 January 2021
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inferred from DOI database lookup
Analysis of the transcriptional program induced by Raf in epithelial cells
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1
1 reference
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7 January 2021
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inferred from DOI database lookup
A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
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inferred from DOI database lookup
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
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inferred from DOI database lookup
Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Raf signalling
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
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inferred from DOI database lookup
Cytoskeletal changes in cell transformation and tumorigenesis
1 reference
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7 January 2021
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inferred from DOI database lookup
Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells
1 reference
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7 January 2021
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inferred from DOI database lookup
Filamin (280-kDa Actin-binding Protein) Is a Caspase Substrate and Is Also Cleaved Directly by the Cytotoxic T Lymphocyte Protease Granzyme B during Apoptosis
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
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The p150-Spir protein provides a link between c-Jun N-terminal kinase function and actin reorganization
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
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inferred from DOI database lookup
The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
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inferred from DOI database lookup
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 protects epithelial cells against anoikis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ezrin is a cyclic AMP-dependent protein kinase anchoring protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
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Snail/slug family of repressors: slowly going into the fast lane of development and cancer
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
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Evidence for a function of CtBP in epithelial gene regulation and anoikis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
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Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900251-9
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7 January 2021
based on heuristic
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Identifiers
DOI
10.1016/S0955-0674(00)00251-9
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1246615
OpenCitations bibliographic resource ID
1246615
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1246615
PubMed publication ID
11544023
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1246615
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