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Cell-substrate interactions and signaling through ILK
scientific article (publication date: April 2000)
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scholarly article
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review article
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Europe PubMed Central
title
Cell-substrate interactions and signaling through ILK
(English)
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author name string
S Dedhar
series ordinal
1
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language of work or name
English
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publication date
April 2000
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published in
Current Opinion in Cell Biology
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volume
12
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issue
2
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page(s)
250-6
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cites work
Genetic analyses of integrin function in mice
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Integrin signaling
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Integrin signaling and cell growth control
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Integrins, oncogenes, and anchorage independence.
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Rho GTPases
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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Integrin-mediated signals regulated by members of the rho family of GTPases
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Activation of Rac and Cdc42 by integrins mediates cell spreading
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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Role of Rho in chemoattractant-activated leukocyte adhesion through integrins
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Integrin activation by R-ras.
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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Integrin cytoplasmic interactions and bidirectional transmembrane signalling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Control of adhesion-dependent cell survival by focal adhesion kinase
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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The adaptor protein Shc couples a class of integrins to the control of cell cycle progression
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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Integrin-mediated activation of MEK and mitogen-activated protein kinase is independent of Ras [corrected].
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell motility by mitogen-activated protein kinase
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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Anchorage-dependent cell cycle progression
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of anoikis: MEKK-1 activation requires cleavage by caspases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of pp125FAK in cultured fibroblasts results in apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms and consequences of activation of protein kinase B/Akt
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
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inferred from DOI database lookup
Regulation of cell death protease caspase-9 by phosphorylation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-linked kinase (ILK): a regulator of integrin and growth-factor signalling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vinculin is essential for muscle function in the nematode
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction through beta-catenin and specification of cell fate during embryogenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stabilization of beta-catenin by genetic defects in melanoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cadherins and catenins in development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A causal role for E-cadherin in the transition from adenoma to carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autocrine TGF-beta-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the integrin-linked kinase (ILK) in mouse skin: loss of expression in suprabasal layers of the epidermis and up-regulation by erbB-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ILK (beta1-integrin-linked protein kinase): a novel immunohistochemical marker for Ewing's sarcoma and primitive neuroectodermal tumour
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900083-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0955-0674(99)00083-6
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PubMed publication ID
10712922
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