(Q47074406)

title

Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism (English)

1 reference

5 January 2018

main subject

Integrin linked kinase

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positive regulation of signal transduction

GOA release 2020-03-11

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GOA release 2020-03-11

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D K Lynch

1

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5 January 2018

C A Ellis

series ordinal

2

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5 January 2018

P A Edwards

series ordinal

3

1 reference

5 January 2018

I D Hiles

series ordinal

4

1 reference

5 January 2018

language of work or name

English

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publication date

1 December 1999

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5 January 2018

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5 January 2018

volume

18

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5 January 2018

page(s)

8024-8032

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5 January 2018

issue

56

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5 January 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203258

exact match

0 references

cites work

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

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7 January 2021

Role of translocation in the activation and function of protein kinase B

1 reference

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7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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7 January 2021

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

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7 January 2021

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

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7 January 2021

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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7 January 2021

Akt activation by growth factors is a multiple-step process: the role of the PH domain

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7 January 2021

The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

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7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

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7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

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7 January 2021

The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP

1 reference

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7 January 2021

BCL-2 family: regulators of cell death

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7 January 2021

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

PDK1, one of the missing links in insulin signal transduction?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

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7 January 2021

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis

1 reference

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7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

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7 January 2021

Characterization of a naturally occurring ErbB4 isoform that does not bind or activate phosphatidyl inositol 3-kinase

1 reference

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7 January 2021

Dual role for adenine nucleotides in the regulation of the atrial natriuretic peptide receptor, guanylyl cyclase-A.

1 reference

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7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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7 January 2021

Disruption of epithelial cell-matrix interactions induces apoptosis

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7 January 2021

Integrins and anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Stimulation of IRS-1-associated phosphatidylinositol 3-kinase and Akt/protein kinase B but not glucose transport by beta1-integrin signaling in rat adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

1 reference

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7 January 2021

Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation

1 reference

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7 January 2021

A time-efficient, linear-space local similarity algorithm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Crystal structure of the tyrosine kinase domain of the human insulin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Regulation of protein kinase cascades by protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Two erbB-4 transcripts are expressed in normal breast and in most breast cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203258

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203258

1 reference

5 January 2018

1 reference

5 January 2018