Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q57274134)
Watch
English
Apaf-1 is a transcriptional target for E2F and p53
No description defined
In more languages
edit
Statements
instance of
scholarly article
0 references
title
Apaf-1 is a transcriptional target for E2F and p53
(English)
0 references
author
Francesco Cecconi
object named as
Francesco Cecconi
series ordinal
6
0 references
Kristian Helin
object named as
Kristian Helin
series ordinal
8
0 references
author name string
M. Cristina Moroni
series ordinal
1
0 references
Emma S. Hickman
series ordinal
2
0 references
Eros Lazzerini Denchi
series ordinal
3
0 references
Greta Caprara
series ordinal
4
0 references
Elena Colli
series ordinal
5
0 references
Heiko Müller
series ordinal
7
0 references
publication date
June 2001
0 references
published in
Nature Cell Biology
0 references
volume
3
0 references
page(s)
552-558
0 references
issue
6
0 references
exact match
https://scigraph.springernature.com/pub.10.1038/35078527
0 references
cites work
Cancer cell cycles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Hallmarks of Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma gene family in differentiation and development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of E2F by pRB-family proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and E2F-1 cooperate to mediate apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1-induced p53-independent apoptosis in transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for the p53 homologue p73 in E2F-1-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p14ARF links the tumour suppressors RB and p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor surveillance via the ARF-p53 pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p73 is a simian [correction of human] p53-related protein that can induce apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biochemistry of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9 and APAF-1 form an active holoenzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A matter of life and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the cyclin E gene by transcription factor E2F1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogene-dependent apoptosis is mediated by caspase-9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/35078527
0 references
PubMed ID
11389439
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
