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Caspase-9 and APAF-1 form an active holoenzyme
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
title
Caspase-9 and APAF-1 form an active holoenzyme
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
author name string
J Rodriguez
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
Y Lazebnik
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
publication date
1 December 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
published in
Genes & Development
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
volume
13
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
page(s)
3179-3184
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
issue
24
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
cites work
Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Caspase-9 can be activated without proteolytic processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Oncogene-dependent apoptosis is mediated by caspase-9.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
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13 July 2018
Essential role of CED-4 oligomerization in CED-3 activation and apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
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13 July 2018
Caspases: enemies within
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
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13 July 2018
Differential requirement for caspase 9 in apoptotic pathways in vivo.
1 reference
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PubMed Central
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13 July 2018
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Autoproteolytic activation of pro-caspases by oligomerization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
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13 July 2018
Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
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13 July 2018
An induced proximity model for caspase-8 activation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
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13 July 2018
Temporal and spatial control of the adenovirus proteinase by both a peptide and the viral DNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
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13 July 2018
Surface-dependent hemostasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
13 July 2018
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317200
retrieved
26 September 2018
Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10617566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/GAD.13.24.3179
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
PMCID
317200
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
PubMed ID
10617566
1 reference
stated in
Europe PubMed Central
PubMed ID
10617566
retrieved
7 August 2017
ResearchGate publication ID
247610059
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