(Q36637874)

15 August 2017

1 reference

title

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription (English)

1 reference

15 August 2017

1 reference

Claus Scheidereit

1

1 reference

PubMed ID

17072322

15 August 2017

language of work or name

English

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publication date

1 October 2006

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15 August 2017

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15 August 2017

25

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15 August 2017

6685-6705

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15 August 2017

51

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209934

15 August 2017

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cites work

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

NEMO trimerizes through its coiled-coil C-terminal domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase alpha and p65/RelA contribute to optimal epidermal growth factor-induced c-fos gene expression independent of IkappaBalpha degradation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Latent membrane protein 1 of Epstein-Barr virus stimulates processing of NF-kappa B2 p100 to p52.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Identification of the familial cylindromatosis tumour-suppressor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

In vivo identification of inducible phosphoacceptors in the IKKgamma/NEMO subunit of human IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Shaping the nuclear action of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Ubiquitin signalling in the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Transient IkappaB kinase activity mediates temporal NF-kappaB dynamics in response to a wide range of tumor necrosis factor-alpha doses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Inhibition of NF-kappaB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

CD40 regulates the processing of NF-kappaB2 p100 to p52

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Zebrafish IkappaB kinase 1 negatively regulates NF-kappaB activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

NEMO/IKK gamma: linking NF-kappa B to human disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kappaB2 to p52 via an IKKgamma/NEMO-independent signalling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Cardif: a protein central to innate immunity is inactivated by the HCV NS3 serine protease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

KSHV vFLIP binds to IKK-gamma to activate IKK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Human T-lymphotropic virus type I tax activates I-kappa B kinase by inhibiting I-kappa B kinase-associated serine/threonine protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Missing pieces in the NF-kappaB puzzle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Convergent actions of I kappa B kinase beta and protein kinase C delta modulate mRNA stability through phosphorylation of 14-3-3 beta complexed with tristetraprolin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Ubiquitylation and cell signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

An alternative splice product of IkappaB kinase (IKKgamma), IKKgamma-delta, differentially mediates cytokine and human T-cell leukemia virus type 1 tax-induced NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

NF-kappaB and the innate immune response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

SUMO: a history of modification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Signaling to NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

CSN3 interacts with IKKgamma and inhibits TNF- but not IL-1-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IKKalpha controls formation of the epidermis independently of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Tyrosine Phosphorylation of I-κB Kinase α/β by Protein Kinase C-Dependent c-Src Activation Is Involved in TNF-α-Induced Cyclooxygenase-2 Expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

PIDD mediates NF-kappaB activation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Effects of IL-1 receptor-associated kinase (IRAK) expression on IL-1 signaling are independent of its kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of beta-catenin function by the IkappaB kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Ikappab kinase-beta (ikkbeta) modulation of epithelial sodium channel activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

CIKS, a connection to Ikappa B kinase and stress-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Act1, an NF-kappa B-activating protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation of alternative NF-kappa B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Role of the adaptor protein CIKS in the activation of the IKK complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

A novel ubiquitin-like domain in IkappaB kinase beta is required for functional activity of the kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Characterization of the Ikappa B-kinase NEMO binding domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Complete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-kappaB pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Lymphotoxin beta receptor induces sequential activation of distinct NF-kappa B factors via separate signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

A dual role for Ikk alpha in tooth development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Helicobacter pylori activates NF-kappaB via the alternative pathway in B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Fanconi anemia protein complex is a novel target of the IKK signalsome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Vav-1 and the IKK alpha subunit of I kappa B kinase functionally associate to induce NF-kappa B activation in response to CD28 engagement.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The ATM protein is required for sustained activation of NF-kappaB following DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Stress-induced inhibition of the NF-kappaB signaling pathway results from the insolubilization of the IkappaB kinase complex following its dissociation from heat shock protein 90.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Two pathways to NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

vCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Act1, a negative regulator in CD40- and BAFF-mediated B cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Negative regulation of JNK signaling by the tumor suppressor CYLD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of T cell development by the deubiquitinating enzyme CYLD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Towards a proteome-scale map of the human protein–protein interaction network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Modulation of NF-kappaB activity by exchange of dimers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Two carboxyl-terminal activation regions of Epstein-Barr virus latent membrane protein 1 activate NF-kappaB through distinct signaling pathways in fibroblast cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Essential function for the kinase TAK1 in innate and adaptive immune responses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of IkappaB kinase (IKK) complex by IKKgamma-dependent phosphorylation of the T-loop and C terminus of IKKbeta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Inhibition of nuclear factor kappaB activity by viral interferon regulatory factor 3 of Kaposi's sarcoma-associated herpesvirus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Control of lymphocyte development by nuclear factor-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

NF-kappaB signaling pathways in mammalian and insect innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TRUSS, a Novel Tumor Necrosis Factor Receptor 1 Scaffolding Protein That Mediates Activation of the Transcription Factor NF-κB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Tetrameric oligomerization of IkappaB kinase gamma (IKKgamma) is obligatory for IKK complex activity and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IKK alpha regulates estrogen-induced cell cycle progression by modulating E2F1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Nuclear role of I kappa B Kinase-gamma/NF-kappa B essential modulator (IKK gamma/NEMO) in NF-kappa B-dependent gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The putative oncoprotein Bcl-3 induces cyclin D1 to stimulate G(1) transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

TRAF2: a double-edged sword?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

IkappaB kinases: key regulators of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The zinc finger mutation C417R of I-kappa B kinase gamma impairs lipopolysaccharide- and TNF-mediated NF-kappa B activation through inhibiting phosphorylation of the I-kappa B kinase beta activation loop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The essential role of MEKK3 in TNF-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Activation of IKK by thymosin alpha1 requires the TRAF6 signalling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209934

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209934

1 reference

15 August 2017

1 reference

PubMed ID

17072322