(Q34354320)

1 August 2017

title

PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages (English)

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1 August 2017

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Jean Marie Bruey

1

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1 August 2017

Nathalie Bruey-Sedano

2

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1 August 2017

Ruchi Newman

3

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1 August 2017

Sharon Chandler

4

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1 August 2017

Christian Stehlik

5

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1 August 2017

John C Reed

6

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1 August 2017

language of work or name

English

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publication date

28 September 2004

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Journal of Biological Chemistry

1 August 2017

published in

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1 August 2017

volume

279

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1 August 2017

issue

50

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1 August 2017

page(s)

51897-51907

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PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases.

1 August 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

The PYRIN domain: a member of the death domain-fold superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

The PYRIN domain: a novel motif found in apoptosis and inflammation proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

NALPs: a novel protein family involved in inflammation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Comparative analysis of apoptosis and inflammation genes of mice and humans

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta

21 January 2018

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CLAN, a novel human CED-4-like gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Isotypic variants of the interferon-inducible transcriptional repressor IFI 16 arise through differential mRNA splicing

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

The interferon in TLR signaling: more than just antiviral

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

NF-kappaB regulation in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

NF-kappaB signaling pathways in mammalian and insect innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Epigenetic inactivation of TMS1/ASC in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

ASC/TMS1, a caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

Effects of methylation on expression of TMS1/ASC in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

21 January 2018

Inflammation and cancer

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https://api.crossref.org/works/10.1074%2FJBC.M406741200

Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406741200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406741200

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1 August 2017

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