(Q28206764)

Toll-like receptors and innate immunity

21 January 2018

1 reference

MyD88, an adapter protein involved in interleukin-1 signaling

21 January 2018

1 reference

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

21 January 2018

1 reference

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

21 January 2018

1 reference

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

21 January 2018

1 reference

TIRAP: an adapter molecule in the Toll signaling pathway

21 January 2018

1 reference

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

1 reference

Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains

21 January 2018

1 reference

Nods: a family of cytosolic proteins that regulate the host response to pathogens

21 January 2018

1 reference

Genetic control of MHC class II expression

21 January 2018

1 reference

The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation

21 January 2018

1 reference

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

21 January 2018

1 reference

The leucine-rich repeat as a protein recognition motif

21 January 2018

1 reference

Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity

21 January 2018

1 reference

Two distinct domains within CIITA mediate self-association: involvement of the GTP-binding and leucine-rich repeat domains

21 January 2018

1 reference

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

21 January 2018

1 reference

Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB

21 January 2018

1 reference

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

Human Nod1 confers responsiveness to bacterial lipopolysaccharides

21 January 2018

1 reference

CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.

21 January 2018

1 reference

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

21 January 2018

1 reference

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

CARD15 mutations in Blau syndrome

21 January 2018

1 reference

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

21 January 2018

1 reference

CLAN, a novel human CED-4-like gene

21 January 2018

1 reference

Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis

21 January 2018

1 reference

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

21 January 2018

1 reference

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

21 January 2018

1 reference

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

The neuronal apoptosis inhibitory protein (Naip) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila.

21 January 2018

1 reference

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases.

21 January 2018

1 reference

PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

21 January 2018

1 reference

Imprinting in clusters: lessons from Beckwith-Wiedemann syndrome

21 January 2018

1 reference

Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

21 January 2018

1 reference

A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis

21 January 2018

1 reference

The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation

21 January 2018

1 reference

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis

21 January 2018

1 reference

TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.

21 January 2018

1 reference

CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways

21 January 2018

1 reference

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

21 January 2018

1 reference

Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

21 January 2018

1 reference

Oocyte-specific genes regulate follicle formation, fertility and early mouse development

21 January 2018

1 reference

Mater, a maternal effect gene required for early embryonic development in mice

21 January 2018

1 reference

A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta

21 January 2018

1 reference

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

21 January 2018

1 reference

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

21 January 2018

1 reference

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

21 January 2018

1 reference

Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

1 reference

ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils

21 January 2018

1 reference

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

1 reference

Molecular cloning of the interleukin-1 beta converting enzyme

21 January 2018

1 reference

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

21 January 2018

1 reference

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

21 January 2018

1 reference

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

21 January 2018

1 reference

The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy

21 January 2018

1 reference

Structure-function analysis of the Shigella virulence factor IpaB.

21 January 2018

1 reference

The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1

21 January 2018

1 reference

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

Natural adjuvants: endogenous activators of dendritic cells

21 January 2018

1 reference

The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway

21 January 2018

1 reference

The danger model: a renewed sense of self

21 January 2018

1 reference

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

21 January 2018

1 reference

Caspase-1 (interleukin-1β-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9

21 January 2018

1 reference

Modulators of inflammation use nuclear factor-kappa B and activator protein-1 sites to induce the caspase-1 and granzyme B inhibitor, proteinase inhibitor 9.

21 January 2018

1 reference

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

21 January 2018

1 reference

New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes

21 January 2018

1 reference

Hereditary periodic fever syndromes.

21 January 2018

1 reference

A candidate gene for familial Mediterranean fever

21 January 2018

1 reference

Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

21 January 2018

1 reference

Genetic linkage of the Muckle-Wells syndrome to chromosome 1q44.

21 January 2018

1 reference

An autosomal dominant periodic fever associated with AA amyloidosis in a north Indian family maps to distal chromosome 1q.

21 January 2018

1 reference

Identification of a locus on chromosome 1q44 for familial cold urticaria

21 January 2018

1 reference

A novel domain within the 55 kd TNF receptor signals cell death

21 January 2018

1 reference

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

21 January 2018

1 reference

The CARD domain: a new apoptotic signalling motif

21 January 2018

1 reference

The PYRIN domain: a novel motif found in apoptosis and inflammation proteins

21 January 2018

1 reference

The DAPIN family: a novel domain links apoptotic and interferon response proteins

21 January 2018

1 reference

Transcription and growth regulatory functions of the HIN-200 family of proteins

21 January 2018

1 reference

A human homologue of mouse Mater, a maternal effect gene essential for early embryonic development

21 January 2018

1 reference

Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

21 January 2018

1 reference

Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein).

21 January 2018

1 reference

The bare lymphocyte syndrome and the regulation of MHC expression

21 January 2018

1 reference

The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense

21 January 2018

1 reference

Genetic and physical mapping of the mouse host resistance locus Lgn1

31 March 2020

1 reference

Expression of apoptosis-associated speck-like protein containing a caspase recruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues

31 March 2020

1 reference

31 March 2020

1 reference