(Q24548385)

English

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11158290%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11158290%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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protein ubiquitination

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

Vigo Heissmeyer

1

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3 November 2019

Daniel Krappmann

2

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3 November 2019

author name string

E N Hatada

3

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3 November 2019

C Scheidereit

4

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3 November 2019

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publication date

1 February 2001

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3 November 2019

Molecular and Cellular Biology

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3 November 2019

21

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3 November 2019

1024-1035

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3 November 2019

4

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3 November 2019

SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

1 reference

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NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

1 reference

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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

1 reference

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24 March 2017

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

1 reference

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24 March 2017

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

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Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

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I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

1 reference

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

1 reference

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Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

1 reference

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Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha

1 reference

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Three-dimensional structure of a complex between the death domains of Pelle and Tube

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling

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24 March 2017

Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination

1 reference

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Aberrant rel/nfkb genes and activity in human cancer

1 reference

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24 March 2017

beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99557

24 March 2017

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

1 reference

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24 March 2017

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

1 reference

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24 March 2017

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

1 reference

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24 March 2017

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

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7 April 2017

NF-kappa B: ten years after

1 reference

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7 April 2017

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99557

7 April 2017

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99557

7 April 2017

The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

1 reference

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7 April 2017

Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production

1 reference

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27 September 2017

The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance

1 reference

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NF-kappaB and the innate immune response

1 reference

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27 September 2017

Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1.

1 reference

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Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain

1 reference

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27 September 2017

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

1 reference

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27 September 2017

IkappaBalpha ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, betaTrCP1 and betaTrCP2.

1 reference

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Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

1 reference

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Alternative splicing variants of IkappaB beta establish differential NF-kappaB signal responsiveness in human cells

1 reference

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27 September 2017

Enzymes catalyzing ubiquitination and proteolytic processing of the p105 precursor of nuclear factor kappaB1.

1 reference

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The complete exon-intron structure of the 156-kb human gene NFKB1, which encodes the p105 and p50 proteins of transcription factors NF-kappa B and I kappa B-gamma: implications for NF-kappa B-mediated signal transduction

1 reference

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27 September 2017

A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit

1 reference

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27 September 2017

Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99557

27 September 2017

Activation of NF-kappa B in vivo is regulated by multiple phosphorylations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99557

27 September 2017

Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB.

1 reference

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The NF-kappa B/Rel and I kappa B gene families: mediators of immune response and inflammation

1 reference

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Proteolytic processing of NF-kappa B/I kappa B in human monocytes. ATP-dependent induction by pro-inflammatory mediators

1 reference

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Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation

1 reference

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The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.

1 reference

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The generation of nfkb2 p52: mechanism and efficiency

1 reference

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Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99557

30 May 2018

Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome

1 reference

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Signal transduction through NF-kappa B.

1 reference

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Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase

1 reference

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30 May 2018

p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction

1 reference

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The death domain: a module shared by proteins with diverse cellular functions.

1 reference

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30 May 2018

Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway.

1 reference

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30 May 2018

1.3E2, a variant of the B lymphoma 70Z/3, defective in activation of NF-?B and OTF-2

1 reference

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30 May 2018

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/11158290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/11158290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.21.4.1024-1035.2001

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11158290%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11158290%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11158290%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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