(Q47965199)

English

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.

scientific article published in March 1999

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scholarly article

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin. (English)

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

phosphorylation

1 reference

based on heuristic

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author name string

S Y Fuchs

1

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

A Chen

2

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

Y Xiong

3

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

Z Q Pan

4

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

Z Ronai

5

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

language of work or name

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publication date

1 March 1999

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

18

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

2039-2046

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

12

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202760

0 references

beta-catenin is a target for the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

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21 January 2018

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

1 reference

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21 January 2018

MEKK1/JNK signaling stabilizes and activates p53.

1 reference

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21 January 2018

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

1 reference

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21 January 2018

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro

1 reference

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21 January 2018

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.

1 reference

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21 January 2018

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

1 reference

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21 January 2018

Proteins with leucine-rich repeats

1 reference

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21 January 2018

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

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21 January 2018

Proteolysis and the G1-S transition: the SCF connection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

The ancient regulatory-protein family of WD-repeat proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor

1 reference

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21 January 2018

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

NF-kappaB activation: the I kappaB kinase revealed?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Beta-catenin: a key mediator of Wnt signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

21 January 2018

The role of protein stability in the cell cycle and cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

7 January 2021

based on heuristic

inferred from DOI database lookup

Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappa B: a lesson in family values

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

7 January 2021

based on heuristic

inferred from DOI database lookup

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202760

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1202760

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

1 reference

Europe PubMed Central

7 February 2018

http://europepmc.org/abstract/MED/10321728

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