(Q24290608)

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vCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgamma

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vCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgamma (English)

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Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

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GOA release 2020-03-11

protein-containing complex assembly

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GOA release 2020-03-11

author name string

J L Poyet

1

author given names

J L

author last names

Poyet

1 reference

31 January 2024

S M Srinivasula

2

author given names

S M

author last names

Srinivasula

1 reference

31 January 2024

E S Alnemri

3

author given names

E S

author last names

Alnemri

1 reference

31 January 2024

language of work or name

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publication date

2 February 2001

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Journal of Biological Chemistry

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276

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5

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3183-7

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CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis

1 reference

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21 January 2018

CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10

1 reference

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c-E10 is a caspase-recruiting domain-containing protein that interacts with components of death receptors signaling pathway and activates nuclear factor-kappaB

1 reference

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21 January 2018

Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Molecular determinants of NF-kappaB-inducing kinase action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Regulation of the NF-kappaB activation pathway by isolated domains of FIP3/IKKgamma, a component of the IkappaB-alpha kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Synthetic activation of caspases: artificial death switches

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

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HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Regulation of gene expression by HTLV-I Tax protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Anti-apoptotic strategies of lymphotropic viruses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

The multisubunit IkappaB kinase complex shows random sequential kinetics and is activated by the C-terminal domain of IkappaB alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000792200

21 January 2018

Identifiers

10.1074/JBC.C000792200

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