(Q21112275)

English

Endothelin 2

mammalian protein found in Homo sapiens

PPET2
preproendothelin 2
Preproendothelin-2
endothelin-2
EDN2

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20800

Endothelin-like toxin family

1 reference

based on heuristic

inferred from protein domain or family

Endothelin-like toxin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

hormone activity

determination method

1 reference

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

endothelin B receptor binding

determination method

1 reference

8 April 2019

Cloning and functional expression of human cDNA for the ETB endothelin receptor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

intracellular anatomical structure

determination method

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20800&geneProductId=UniProtKB:P20800

determination method

extracellular space

determination method

1 reference

8 April 2019

Ursodeoxycholic acid reduces increased circulating endothelin 2 in primary biliary cirrhosis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

biological process

positive regulation of prostaglandin-endoperoxide synthase activity

determination method

2 references

8 April 2019

Prostaglandin endoperoxide synthase-2 contributes to the endothelin/sarafotoxin-induced prostaglandin E2 synthesis in mouse osteoblastic cells (MC3T3-E1): evidence for a protein tyrosine kinase-signaling pathway and involvement of protein kinase C

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

hormonal regulation of the force of heart contraction

determination method

1 reference

8 April 2019

Positive inotropic effect of endothelin-2 on human atrium preparations in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

regulation of systemic arterial blood pressure by endothelin

determination method

1 reference

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

vasoconstriction

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

8 April 2019

Characterization of endothelin receptors in the human umbilical artery and vein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

cytokine-mediated signaling pathway

determination method

1 reference

8 April 2019

Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

positive regulation of cytosolic calcium ion concentration

determination method

1 reference

8 April 2019

Effects of endothelins on signal transduction and proliferation in human melanocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

neutrophil chemotaxis

determination method

1 reference

8 April 2019

The involvement of protein kinase G in stimulation of neutrophil migration by endothelins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

positive regulation of heart rate

determination method

1 reference

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

positive regulation of leukocyte chemotaxis

determination method

1 reference

8 April 2019

The involvement of protein kinase G in stimulation of neutrophil migration by endothelins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

cell surface receptor signaling pathway

determination method

1 reference

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

macrophage chemotaxis

determination method

1 reference

8 April 2019

Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

regulation of vasoconstriction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

positive regulation of cell population proliferation

determination method

1 reference

8 April 2019

Effects of endothelins on signal transduction and proliferation in human melanocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

artery smooth muscle contraction

determination method

1 reference

8 April 2019

Characterization of endothelin receptors in the human umbilical artery and vein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

energy homeostasis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

macrophage activation

determination method

1 reference

8 April 2019

Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

prostaglandin biosynthetic process

determination method

2 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

8 April 2019

Prostaglandin endoperoxide synthase-2 contributes to the endothelin/sarafotoxin-induced prostaglandin E2 synthesis in mouse osteoblastic cells (MC3T3-E1): evidence for a protein tyrosine kinase-signaling pathway and involvement of protein kinase C

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

lung alveolus development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

temperature homeostasis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

positive regulation of the force of heart contraction by chemical signal

determination method

1 reference

8 April 2019

Positive inotropic effect of endothelin-2 on human atrium preparations in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

inositol phosphate-mediated signaling

determination method

1 reference

8 April 2019

Effects of endothelins on signal transduction and proliferation in human melanocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

positive regulation of smooth muscle contraction

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

calcium-mediated signaling

determination method

1 reference

8 April 2019

Effects of endothelins on signal transduction and proliferation in human melanocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

determination method

Endothelin-like toxin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20800

Endothelin-like toxin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20800

Identifiers

MeSH descriptor ID

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000361668

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000361668

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21112275&oldid=2022949017"