(Q21113671)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q09428

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q09428

ATP-binding cassette subfamily C member 8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q09428

ATP-binding cassette transporter

1 reference

Transporter Classification Database ID

3.A.1.208.4

2 October 2019

hierarchical database ID heuristic

AAA proteins

1 reference

ABC transporter-like, protein family

1 reference

ABC transporter type 1, transmembrane domain, protein family

1 reference

ABC transporter, conserved site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

1 reference

9 May 2019

transmembrane transporter binding

1 reference

9 May 2019

Ankyrin-B regulates Kir6.2 membrane expression and function in heart

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

sulfonylurea receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

1 reference

9 May 2019

ATPase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

1 reference

9 May 2019

ATP-activated inward rectifier potassium channel activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09428&geneProductId=UniProtKB:Q09428

1 reference

1 January 2018

TAS

protein binding

1 reference

21 June 2018

Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09428&geneProductId=UniProtKB:Q09428

potassium channel activity

potassium channel activity

IMP

2 references

Alternating hypoglycemia and hyperglycemia in a toddler with a homozygous p.R1419H ABCC8 mutation: an unusual clinical picture

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

IMP

9 May 2019

Monoallelic ABCC8 mutations are a common cause of diazoxide-unresponsive diffuse form of congenital hyperinsulinism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

IMP

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

cell component

sarcolemma

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

mitochondrion

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

inward rectifying potassium channel

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

1 January 2018

Ankyrin-B regulates Kir6.2 membrane expression and function in heart

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

IDA

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

synaptic vesicle membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

regulation of insulin secretion

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

1 reference

9 May 2019

TAS

signal transduction

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09428&geneProductId=UniProtKB:Q09428

potassium ion transmembrane transport

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

transmembrane transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09428&geneProductId=UniProtKB:Q09428

1 reference

21 June 2018

cellular glucose homeostasis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

female pregnancy

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

memory

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

visual learning

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

response to pH

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

response to zinc ion

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

negative regulation of low-density lipoprotein particle clearance

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

negative regulation of angiogenesis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

response to lipopolysaccharide

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

positive regulation of tumor necrosis factor production

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

response to insulin

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

positive regulation of potassium ion transport

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

negative regulation of insulin secretion

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

negative regulation of neurogenesis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

negative regulation of glial cell proliferation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

negative regulation of wound healing

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

negative regulation of neuroblast migration

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

cellular response to organic substance

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

positive regulation of uterine smooth muscle relaxation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

positive regulation of voltage-gated potassium channel activity

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

positive regulation of tight junction disassembly

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

negative regulation of blood-brain barrier permeability

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

potassium ion transport

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09428

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6801

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6841

language of work or name

English

Transporter Classification Database ID

17 August 2016

Identifiers

MeSH descriptor ID

C577507

subject named as

ABCC8 protein, human

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1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

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3.A.1.208.4

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023