(Q21113883)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20749

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

protein-macromolecule adaptor activity

1 reference

8 April 2019

Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

DNA-binding transcription factor activity

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

transcription factor binding

4 references

8 April 2019

BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

Stimulation of CD30 in anaplastic large cell lymphoma leads to production of nuclear factor-kappaB p52, which is associated with hyperphosphorylated Bcl-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

NF-kappa B-inducible BCL-3 expression is an autoregulatory loop controlling nuclear p50/NF-kappa B1 residence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

6 references

8 April 2019

Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

Regulation of Bcl-3 through interaction with the Lck tyrosine kinase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

1 reference

8 April 2019

A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

Diverse effects of BCL3 phosphorylation on its modulation of NF-kappaB p52 homodimer binding to DNA

Bcl3/NF-kappaB2 complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

8 April 2019

A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

protein-containing complex

1 reference

8 April 2019

A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

regulation of apoptotic process

biological process

1 reference

8 April 2019

BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

1 reference

8 April 2019

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

regulation of DNA binding

1 reference

8 April 2019

Diverse effects of BCL3 phosphorylation on its modulation of NF-kappaB p52 homodimer binding to DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

regulation of transcription, DNA-templated

IEP

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20749&geneProductId=UniProtKB:P20749

T-helper 2 cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

antimicrobial humoral response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

germinal center formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

1 reference

8 April 2019

Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

DNA damage response, signal transduction by p53 class mediator

1 reference

8 April 2019

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

extracellular matrix organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

positive regulation of interferon-gamma production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

marginal zone B cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

positive regulation of translation

1 reference

8 April 2019

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

transcription, DNA-templated

cellular response to DNA damage stimulus

1 reference

8 April 2019

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

humoral immune response mediated by circulating immunoglobulin

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

follicular dendritic cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

defense response to bacterium

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

T-helper 1 type immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

1 reference

8 April 2019

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

maintenance of protein location in nucleus

1 reference

8 April 2019

BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

positive regulation of transcription by RNA polymerase II

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

defense response to protozoan

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

negative regulation of receptor signaling pathway via JAK-STAT

1 reference

8 April 2019

Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

regulation of NIK/NF-kappaB signaling

1 reference

8 April 2019

BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

transcription, DNA-templated

IEP

1 reference

8 April 2019

Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20749

ankyrin repeat-containing domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20749

ankyrin repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20749

Identifiers

MeSH descriptor ID

D000081242

subject named as

B-Cell Lymphoma 3 Protein

0 references

MeSH tree code

D12.776.624.664.700.165

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

21 March 2016

language of work or name

1 reference

21 March 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata