(Q21116606)

http://www.ebi.ac.uk/interpro/protein/Q96BI3

1 reference

13 November 2019

1 reference

13 November 2019

5 references

8 April 2019

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

An alternative spliced mouse presenilin-2 mRNA encodes a novel gamma-secretase inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Cellular localization of Nicastrin affects amyloid beta species production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

An atomic structure of human γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

endoplasmic reticulum membrane

IPI

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96BI3&geneProductId=UniProtKB:Q96BI3

integral component of plasma membrane

1 reference

17 October 2017

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96BI3&geneProductId=UniProtKB:Q96BI3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

IDA

Golgi cisterna membrane

1 reference

8 April 2019

integral component of membrane

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Three-dimensional structure of human γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

An atomic structure of human γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

endoplasmic reticulum

3 references

8 April 2019

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

Three-dimensional structure of human γ-secretase

gamma-secretase complex

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

An atomic structure of human γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

integral component of presynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

ephrin receptor signaling pathway

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

membrane protein ectodomain proteolysis

1 reference

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

positive regulation of apoptotic process

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

Notch receptor processing

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96BI3&geneProductId=UniProtKB:Q96BI3

17 October 2017

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96BI3&geneProductId=UniProtKB:Q96BI3

17 October 2017

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96BI3&geneProductId=UniProtKB:Q96BI3

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96BI3&geneProductId=UniProtKB:Q96BI3

metanephros development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

amyloid precursor protein catabolic process

Notch receptor processing

IMP

Notch signaling pathway

4 references

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

membrane protein intracellular domain proteolysis

IBA

1 reference

1 January 2018

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96BI3&geneProductId=UniProtKB:Q96BI3

Notch receptor processing, ligand-dependent

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96BI3

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016