(Q21117300)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20815

cytochrome P450, E-class, CYP3A

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20815

cytochrome P450, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

oxygen binding

1 reference

9 May 2019

Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of [...]

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

aromatase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

heme binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

monooxygenase activity

Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of [...]

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

9 May 2019

estrogen 16-alpha-hydroxylase activity

1 reference

9 May 2019

Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

cell component

organelle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

intracellular membrane-bounded organelle

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

xenobiotic metabolic process

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

1 reference

9 May 2019

alkaloid catabolic process

1 reference

9 May 2019

Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

oxidative demethylation

1 reference

9 May 2019

Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

lipid hydroxylation

1 reference

9 May 2019

Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

steroid metabolic process

Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of [...]

2 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

9 May 2019

Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

estrogen metabolic process

1 reference

9 May 2019

Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20815

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8804

language of work or name

English

cytochrome P450, conserved site

17 August 2016

has part(s)

1 reference

InterPro Release 71.0