(Q24319114)

cytochrome P450 family 3 subfamily A member 5

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cytochrome P450 family 2 subfamily D member 6

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oxidative demethylation

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author name string

Bojan Lalovic

1

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Brian Phillips

2

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Linda L Risler

3

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William Howald

4

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Danny D Shen

Drug Metabolism and Disposition

5

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language of work or name

English

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publication date

April 2004

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published in

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volume

32

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issue

4

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page(s)

447-54

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cites work

Determination of Oxycodone in Plasma and Identification of a Major Metabolite

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7 January 2021

Codeine and morphine in extensive and poor metabolizers of sparteine: pharmacokinetics, analgesic effect and side effects

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7 January 2021

Relative potency of controlled-release oxycodone and controlled-release morphine in a postoperative pain model

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7 January 2021

High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

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7 January 2021

Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily

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7 January 2021

Opiate receptor binding affected differentially by opiates and opioid peptides

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Mu receptor binding of some commonly used opioids and their metabolites

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The antinociceptive potencies of oxycodone, noroxycodone and morphine after intracerebroventricular administration to rats

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7 January 2021

A clinical study on the use of codeine, oxycodone, dextropropoxyphene, buprenorphine, and pentazocine in cancer pain

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7 January 2021

The pharmacokinetics of oxycodone in uremic patients undergoing renal transplantation.

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Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI)

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7 January 2021

Pharmacokinetic-pharmacodynamic relationships of controlled-release oxycodone

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7 January 2021

Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.

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7 January 2021

Genetic contribution to variable human CYP3A-mediated metabolism

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Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action.

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The use of controlled-release oxycodone for the treatment of chronic cancer pain: a randomized, double-blind study

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7 January 2021

Comparison of CYP2D6 content and metoprolol oxidation between microsomes isolated from human livers and small intestines

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7 January 2021

Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity

1 reference

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7 January 2021

Inhibition by fluoxetine of cytochrome P450 2D6 activity.

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7 January 2021

The visceral and somatic antinociceptive effects of dihydrocodeine and its metabolite, dihydromorphine. A cross-over study with extensive and quinidine-induced poor metabolizers

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7 January 2021

The pharmacokinetics of oxycodone after intravenous injection in adults

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7 January 2021

The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects

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7 January 2021

Diclofenac and oxycodone in treatment of postoperative pain: a double-blind trial

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7 January 2021

Comparison of analgesic efficacy of oxycodone and morphine in postoperative intravenous patient-controlled analgesia

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7 January 2021

Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism

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7 January 2021

Dose-ranging study of oxycodone for chronic pain in advanced cancer

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7 January 2021

Efficacy of oxycodone in neuropathic pain: a randomized trial in postherpetic neuralgia

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7 January 2021

Determination of oxycodone metabolites in urines and feces of several mammalian species

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7 January 2021