Wikidata

(Q21117426)

English

Ubiquitin conjugating enzyme E2 M

mammalian protein found in Homo sapiens

  • ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
  • epididymis secretory sperm binding protein
  • yeast UBC12 homolog
  • ubiquitin carrier protein M
  • UBE2M
  • NEDD8 protein ligase
  • Ubiquitin-conjugating enzyme E2 M
  • NEDD8 carrier protein
  • ubiquitin conjugating enzyme E2M
  • NEDD8-conjugating enzyme Ubc12
  • ubiquitin-protein ligase M
In more languages

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
GOA
curator
UniProt
UniProt protein ID
P61081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation
GOA
curator
UniProt
UniProt protein ID
P61081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8
GOA
curator
UniProt
UniProt protein ID
P61081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1
GOA
curator
UniProt
UniProt protein ID
P61081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.
GOA
curator
UniProt
UniProt protein ID
P61081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Ribosomal proteins are targets for the NEDD8 pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of nucleolar signalling to p53 through NEDDylation of L11
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
retrieved
8 April 2019
stated in
A RING E3–substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61081
determination method
IPI
biological process

Identifiers

 
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