(Q24299638)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

0 references

6

1 reference

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20 March 2020

Brenda Schulman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Vladislav O Sviderskiy

2

object named as

Vladislav O Sviderskiy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

author name string

Daniel C Scott

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Julie K Monda

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

John R Lydeard

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Shein Ei Cho

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

language of work or name

English

0 references

publication date

1 June 2014

1 reference

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20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

157

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

page(s)

1671-1684

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl

20 March 2020

cites work

1 reference

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The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

19 March 2017

1 reference

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Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate

19 March 2017

1 reference

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Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates

19 March 2017

1 reference

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E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

19 March 2017

1 reference

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SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation

19 March 2017

1 reference

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Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

19 March 2017

1 reference

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Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

19 March 2017

1 reference

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Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases

19 March 2017

1 reference

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Systematic analysis and nomenclature of mammalian F-box proteins

19 March 2017

1 reference

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Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

19 March 2017

1 reference

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

19 March 2017

1 reference

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RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

19 March 2017

1 reference

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E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

19 March 2017

1 reference

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Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4247792

A conserved asparagine has a structural role in ubiquitin-conjugating enzymes

19 March 2017

1 reference

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Structural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation Enzymes

19 March 2017

1 reference

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BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4247792

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

19 March 2017

1 reference

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Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface

19 March 2017

1 reference

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Selective Recruitment of an E2 Ubiquitin Complex by an E3 Ubiquitin Ligase

19 March 2017

1 reference

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Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b

19 March 2017

1 reference

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The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation

19 March 2017

1 reference

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Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination

19 March 2017

1 reference

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N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex

19 March 2017

1 reference

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A RING E3–substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases

19 March 2017

1 reference

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A Dual E3 Mechanism for Rub1 Ligation to Cdc53

19 March 2017

1 reference

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Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation

19 March 2017

1 reference

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Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases

19 March 2017

1 reference

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Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1

19 March 2017

1 reference

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RING domain E3 ubiquitin ligases

19 March 2017

1 reference

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Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G

19 March 2017

1 reference

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19 March 2017

1 reference

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Essential role for ubiquitin-ubiquitin-conjugating enzyme interaction in ubiquitin discharge from Cdc34 to substrate

19 March 2017

1 reference

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

19 March 2017

1 reference

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Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation

7 April 2017

1 reference

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Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex

7 April 2017

1 reference

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SUMO chain-induced dimerization activates RNF4.

7 April 2017

1 reference

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Multimodal mechanism of action for the Cdc34 acidic loop: a case study for why ubiquitin-conjugating enzymes have loops and tails

27 September 2017

1 reference

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Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

27 September 2017

1 reference

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Structural regulation of cullin-RING ubiquitin ligase complexes

27 September 2017

1 reference

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Structural assembly of cullin-RING ubiquitin ligase complexes

27 September 2017

1 reference

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The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination

27 September 2017

1 reference

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The acidic tail of the Cdc34 ubiquitin-conjugating enzyme functions in both binding to and catalysis with ubiquitin ligase SCFCdc4.

27 September 2017

1 reference

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Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

27 September 2017

1 reference

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Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail

27 September 2017

1 reference

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A conserved catalytic residue in the ubiquitin-conjugating enzyme family.

27 September 2017

1 reference

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Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain

27 September 2017

1 reference

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The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.

27 September 2017

1 reference

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Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4247792

Association of the disordered C-terminus of CDC34 with a catalytically bound ubiquitin.

30 May 2018

1 reference

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Detection of sequential polyubiquitylation on a millisecond timescale

29 November 2018

1 reference

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Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34.

29 November 2018

1 reference

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UCSF Chimera--a visualization system for exploratory research and analysis

29 November 2018

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7 January 2021

A tissue-specific atlas of mouse protein phosphorylation and expression

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7 January 2021

Structural basis for a reciprocal regulation between SCF and CSN.

1 reference

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7 January 2021

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1

1 reference

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7 January 2021

Systematic and quantitative assessment of the ubiquitin-modified proteome

1 reference

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7 January 2021

Expression, purification, and characterization of the E1 for human NEDD8, the heterodimeric APPBP1-UBA3 complex

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7 January 2021

High-level expression and purification of recombinant SCF ubiquitin ligases

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7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

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7 January 2021

The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1

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7 January 2021

Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 † ‡

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7 January 2021

Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

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7 January 2021

Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity

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7 January 2021

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.

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7 January 2021

The molecular basis of ubiquitin-like protein NEDD8 deamidation by the bacterial effector protein Cif.

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7 January 2021

Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis

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7 January 2021

Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

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7 January 2021

The cyclomodulin cycle inhibiting factor (CIF) alters cullin neddylation dynamics

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7 January 2021

Conservation in the Mechanism of Nedd8 Activation by the Human AppBp1-Uba3 Heterodimer

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7 January 2021

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7 January 2021

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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7 January 2021

Features and development of Coot

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7 January 2021

Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family

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7 January 2021

Pathogenic bacteria target NEDD8-conjugated cullins to hijack host-cell signaling pathways

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7 January 2021

Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3

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7 January 2021

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Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24949976%20AND%20SRC:MED&resulttype=core&format=json