Wikidata

(Q21118337)

English

RANBP2-type and C3HC4-type zinc finger containing 1

mammalian protein found in Homo sapiens

  • ubiquitin conjugating enzyme 7 interacting protein 3
  • ranBP-type and C3HC4-type zinc finger-containing protein 1
  • RING-type E3 ubiquitin transferase HOIL-1
  • RBCK1
  • HOIL-1
  • hepatitis B virus X-associated protein 4
  • RING finger protein 54
  • Ubiquitin-conjugating enzyme 7-interacting protein 3
  • heme-oxidized IRP2 ubiquitin ligase 1
  • RBCC protein interacting with PKC1
  • HBV-associated factor 4
In more languages
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
21 references
retrieved
8 April 2019
stated in
RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
A ubiquitin ligase complex assembles linear polyubiquitin chains
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
Protein interactions of the transcription factor Hoxa1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
Expanding the substantial interactome of NEMO using protein microarrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IPI
cell component
LUBAC complex
determination method or standard
IDA
6 references
retrieved
21 June 2018
stated in
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BYM8&geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
21 June 2018
stated in
Molecular Basis and Regulation of OTULIN-LUBAC Interaction
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BYM8&geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
21 June 2018
stated in
Linear ubiquitination prevents inflammation and regulates immune signalling
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BYM8&geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
21 June 2018
stated in
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BYM8&geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
21 June 2018
stated in
A ubiquitin ligase complex assembles linear polyubiquitin chains
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BYM8&geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
21 June 2018
stated in
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BYM8&geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
LUBAC complex
determination method or standard
IBA
IDA
7 references
retrieved
8 April 2019
stated in
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
Molecular Basis and Regulation of OTULIN-LUBAC Interaction
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
A ubiquitin ligase complex assembles linear polyubiquitin chains
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
Linear ubiquitination prevents inflammation and regulates immune signalling
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IBA
biological process
protein linear polyubiquitination
determination method or standard
IBA
IDA
5 references
retrieved
8 April 2019
stated in
Linear ubiquitination prevents inflammation and regulates immune signalling
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
GOA
curator
UniProt
UniProt protein ID
Q9BYM8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYM8
determination method or standard
IBA

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21118337&oldid=2022973394"