(Q24321825)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1990450

positive regulation of tumor necrosis factor-mediated signaling pathway

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1903265

negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1903382

Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

1 reference

Inhibitor of nuclear factor kappa B kinase subunit beta

1 reference

OPA1 mitochondrial dynamin like GTPase

1 reference

RANBP2-type and C3HC4-type zinc finger containing 1

1 reference

Parkin RBR E3 ubiquitin protein ligase

1 reference

Ring finger protein 31

1 reference

OPA1, mitochondrial dynamin like GTPase

1 reference

Parkin RBR E3 ubiquitin protein ligase

1 reference

Inhibitor of kappaB kinase gamma

1 reference

protein ubiquitination

1 reference

1 reference

17

Daniel Krappmann

0 references

Kamyar Hadian

Kamyar Hadian

5

0 references

Peer-Hendrik Kuhn

Peer-Hendrik Kuhn

10

0 references

Konstanze Winklhofer

Konstanze F Winklhofer

20

0 references

Gunnar Dittmar

Gunnar Dittmar

18

0 references

Stefan F Lichtenthaler

11

Stefan F Lichtenthaler

0 references

Jorg Tatzelt

19

Jörg Tatzelt

0 references

W. Wurst

14

Wolfgang Wurst

0 references

Dietrich Trümbach

15

Dietrich Trümbach

0 references

Regina Peis

7

Regina Peis

0 references

Elisa Motori

Elisa Motori

12

0 references

author name string

Anne Kathrin Müller-Rischart

1

0 references

Anna Pilsl

2

0 references

Patrick Beaudette

3

0 references

Maria Patra

4

0 references

Maria Funke

6

0 references

Alexandra Deinlein

8

0 references

Carolin Schweimer

9

0 references

Silvana Hrelia

13

0 references

Thomas Langer

The role of parkin in familial and sporadic Parkinson's disease

16

0 references

language of work or name

English

0 references

publication date

7 March 2013

0 references

published in

Molecular Cell

0 references

volume

49

0 references

issue

5

0 references

page(s)

908-21

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Diverse ubiquitin signaling in NF-κB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Linear ubiquitination prevents inflammation and regulates immune signalling

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

A ubiquitin ligase complex assembles linear polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Parkin deficiency increases vulnerability to inflammation-related nigral degeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021

Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2013.01.036

7 January 2021