(Q21118375)

http://www.ebi.ac.uk/interpro/protein/Q12874

Matrin/U1-C, C2H2-type zinc finger, protein family

1 reference

Domain of unknown function DUF3449, protein family

1 reference

SF3A3 domain, protein family

1 reference

Splicing factor SF3a60 binding domain, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

6 references

8 April 2019

Dynamic protein-protein interaction wiring of the human spliceosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Global landscape of HIV-human protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

catalytic step 2 spliceosome

IEA

1 reference

8 April 2019

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

4 references

17 October 2017

Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

3 references

5 references

1 January 2018

Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

1 January 2018

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

1 reference

8 April 2019

Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

U2-type precatalytic spliceosome

IDA

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

RNA splicing, via transesterification reactions

IBA

biological process

1 reference

8 April 2019

Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

mRNA splicing, via spliceosome

TAS

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

17 October 2017

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

3 references

1 January 2018

Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

1 January 2018

Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12874&geneProductId=UniProtKB:Q12874

mRNA 3'-splice site recognition

IEA

1 reference

8 April 2019

Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

mRNA splicing, via spliceosome

TAS

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Structure of the human activated spliceosome in three conformational states.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

U2-type prespliceosome assembly

IBA

1 reference

8 April 2019

Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12874