Wikidata

(Q21118512)

English

WT1 transcription factor

mammalian protein found in Homo sapiens

  • Wilms tumor 1
  • WT33
  • Wilms tumor protein isoform Ex4a(+)
  • WT1
  • Wilms tumor protein
  • WT1 protein
  • WT1 proteins
  • WT1 protein, human
In more languages

Statements

molecular function
protein binding
determination method
IPI
8 references
retrieved
8 April 2019
stated in
PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IPI
retrieved
8 April 2019
stated in
Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IPI
retrieved
8 April 2019
stated in
WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IPI
retrieved
8 April 2019
stated in
BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IPI
retrieved
8 April 2019
stated in
The Wilms' tumor suppressor gene WT1 is negatively autoregulated
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IPI
retrieved
8 April 2019
stated in
Repression of Pax-2 by WT1 during normal kidney development
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IPI
retrieved
8 April 2019
stated in
Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
8 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19544&geneProductId=UniProtKB:P19544
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19544&geneProductId=UniProtKB:P19544
determination method
IEA
retrieved
27 March 2018
stated in
Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19544&geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
27 March 2018
stated in
Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19544&geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
27 March 2018
stated in
BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19544&geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
27 March 2018
stated in
WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19544&geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
27 March 2018
stated in
Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19544&geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
27 March 2018
stated in
WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19544&geneProductId=UniProtKB:P19544
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
9 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IEA
retrieved
8 April 2019
stated in
WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IBA
biological process
positive regulation of transcription, DNA-templated
determination method
IDA
IGI
9 references
retrieved
8 April 2019
stated in
WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IGI
retrieved
8 April 2019
stated in
PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
negative regulation of transcription, DNA-templated
determination method
IDA
7 references
retrieved
8 April 2019
stated in
Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiation
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
The Wilms' tumor suppressor gene WT1 is negatively autoregulated
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Repression of Pax-2 by WT1 during normal kidney development
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA
retrieved
8 April 2019
stated in
Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors
GOA
curator
UniProt
UniProt protein ID
P19544
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19544
determination method
IDA

Identifiers

MeSH descriptor ID
C583751
subject named as
WT1 protein, human
0 references
Freebase ID
/m/03cs5ws
0 references
 
edit
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q21118512&oldid=2022974258"