(Q21119607)

http://www.ebi.ac.uk/interpro/protein/O95989

InterPro Release 71.0

reference URL

NUDIX hydrolase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

NUDIX hydrolase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

1 reference

10 September 2018

inositol diphosphate tetrakisphosphate diphosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

1 reference

8 April 2019

inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

1 reference

10 September 2018

diphosphoinositol-polyphosphate diphosphatase activity

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

27 March 2018

27 March 2018

Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

1 reference

10 September 2018

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

1 reference

8 April 2019

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

1 reference

10 September 2018

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

1 reference

10 September 2018

magnesium ion binding

1 reference

8 April 2019

Crystal structure of human diphosphoinositol phosphatase 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

1 reference

10 September 2018

endopolyphosphatase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

bis(5'-adenosyl)-hexaphosphatase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

bis(5'-adenosyl)-pentaphosphatase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

m7G(5')pppN diphosphatase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

diphosphoinositol-polyphosphate diphosphatase activity

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

8 April 2019

8 April 2019

Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

inositol diphosphate pentakisphosphate diphosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

1 reference

8 April 2019

cell component

nucleus

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

biological process

cell-cell signaling

1 reference

8 April 2019

The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

diadenosine polyphosphate catabolic process

1 reference

8 April 2019

The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

inositol phosphate metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

1 reference

8 April 2019

diphosphoinositol polyphosphate catabolic process

1 reference

8 April 2019

Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

diadenosine pentaphosphate catabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

diadenosine hexaphosphate catabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

adenosine 5'-(hexahydrogen pentaphosphate) catabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

diphosphoinositol polyphosphate metabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

http://www.uniprot.org/uniprot/O95989.txt?version=144

EC enzyme number

3.6.1.-

1 reference

14 November 2015

has part(s)

NUDIX hydrolase domain

1 reference

http://www.ebi.ac.uk/interpro/protein/O95989

InterPro Release 71.0

reference URL

NUDIX hydrolase, conserved site

1 reference