(Q22010421)

English

The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein

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scholarly article

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The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein (English)

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Saccharomyces cerevisiae

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P(1),P(6)-bis(5'-adenosyl)hexaphosphate

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ChEBI release 2020-05-28

Nudix hydrolase 3

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GOA release 2020-03-11

diadenosine polyphosphate catabolic process

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GOA release 2020-03-11

Polyphosphatase DDP1 YOR163W

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GOA release 2020-03-11

Schizosaccharomyces pombe

object named as

Schizosaccharomyces pombe

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based on heuristic

inferred from title

author name string

S T Safrany

1

author given names

S T

author last names

Safrany

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7 February 2023

S W Ingram

2

author given names

S W

author last names

Ingram

1 reference

7 February 2023

J L Cartwright

3

author given names

J L

author last names

Cartwright

1 reference

7 February 2023

J R Falck

4

author given names

J R

author last names

Falck

1 reference

7 February 2023

A G McLennan

5

author given names

A G

author last names

McLennan

1 reference

7 February 2023

L D Barnes

6

author given names

L D

author last names

Barnes

1 reference

7 February 2023

S B Shears

7

author given names

S B

author last names

Shears

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7 February 2023

language of work or name

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publication date

30 July 1999

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Journal of Biological Chemistry

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274

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21735-40

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31

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The neurotransmitter role of diadenosine polyphosphates.

1 reference

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21 January 2018

Diadenosine oligophosphates (Ap(n)A), a novel class of signalling molecules?

1 reference

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21 January 2018

Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator"

1 reference

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21 January 2018

Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit

1 reference

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21 January 2018

Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase

1 reference

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21 January 2018

Opposite effects of cell differentiation and apoptosis on Ap3A/Ap4A ratio in human cell cultures

1 reference

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21 January 2018

Diadenosine 5',5"-P1,P5-pentaphosphate harbors the properties of a signaling molecule in the heart.

1 reference

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21 January 2018

Intracellular diadenosine polyphosphates: a novel family of inhibitory ligands of the ATP-sensitive K+ channel.

1 reference

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21 January 2018

Adenosine(5')hexaphospho(5')adenosine stimulation of a Ca(2+)-induced Ca(2+)-release channel from skeletal muscle sarcoplasmic reticulum

1 reference

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21 January 2018

Adenine dinucleotides: a novel class of signalling molecules

1 reference

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21 January 2018

Alteration of adenyl dinucleotide metabolism by environmental stress

1 reference

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21 January 2018

Inhibition of protein kinase activity of phorboid and ingenoid receptor by di(adenosine-5')oligophosphate.

1 reference

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21 January 2018

The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

1 reference

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21 January 2018

Human diadenosine 5',5"'-P1,P4-tetraphosphate pyrophosphohydrolase is a member of the MutT family of nucleotide pyrophosphatases

1 reference

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21 January 2018

Cloning and expression of diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase from Lupinus angustifolius L.

1 reference

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21 January 2018

The gene, ialA, associated with the invasion of human erythrocytes by Bartonella bacilliformis, designates a nudix hydrolase active on dinucleoside 5'-polyphosphates.

1 reference

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21 January 2018

Schizosaccharomyces pombe Aps1, a diadenosine 5',5' "-P1, P6-hexaphosphate hydrolase that is a member of the nudix (MutT) family of hydrolases: cloning of the gene and characterization of the purified enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5"'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

Turnover of inositol pentakisphosphates, inositol hexakisphosphate and diphosphoinositol polyphosphates in primary cultured hepatocytes

1 reference

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21 January 2018

Turnover of bis-diphosphoinositol tetrakisphosphate in a smooth muscle cell line is regulated by beta2-adrenergic receptors through a cAMP-mediated, A-kinase-independent mechanism

1 reference

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21 January 2018

Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

Identification and purification of diphosphoinositol pentakisphosphate kinase, which synthesizes the inositol pyrophosphate bis(diphospho)inositol tetrakisphosphate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

Purification and crystallization of complexes modeling the active state of the fragile histidine triad protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

Cloning of the Schizosaccharomyces pombe gene encoding diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) asymmetrical hydrolase: sequence similarity with the histidine triad (HIT) protein family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

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21 January 2018

Inositol hexakisphosphate in Schizosaccharomyces pombe: synthesis from Ins(1,4,5)P3 and osmotic regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

The interaction of coatomer with inositol polyphosphates is conserved in Saccharomyces cerevisiae

1 reference

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21 January 2018

On the origin of enzymatic species

1 reference

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21 January 2018

The P-loop--a common motif in ATP- and GTP-binding proteins

1 reference

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21 January 2018

Large-scale protein structure modeling of the Saccharomyces cerevisiae genome

1 reference

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21 January 2018

Diadenosine phosphates and the physiological control of blood pressure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21735

21 January 2018

The IalA invasion gene of Bartonella bacilliformis encodes a (de)nucleoside polyphosphate hydrolase of the MutT motif family and has homologs in other invasive bacteria

1 reference

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Isolation and characterization of dinucleoside tetra- and tri-phosphates formed in the presence of lysyl-sRNA synthetase

1 reference

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Regulation of ryanodine receptor calcium release channels by diadenosine polyphosphates.

1 reference

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Cyclooxygenase regulates human oropharyngeal carcinomas via the proinflammatory cytokine IL-6: a general role for inflammation?

1 reference

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Diadenosine polyphosphates evoke Ca2+ transients in guinea-pig brain via receptors distinct from those for ATP

1 reference

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The role of the FHIT/FRA3B locus in cancer

1 reference

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Diadenosine polyphosphates. A novel class of glucose-induced intracellular messengers in the pancreatic beta-cell

1 reference

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Identifiers

10.1074/JBC.274.31.21735

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