Wikidata

(Q21119880)

English

Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1

mammalian protein found in Homo sapiens

  • KIR2DL1/3DL2
  • p58 NK cell inhibitory receptor NKR-K6
  • MHC class I NK cell receptor
  • CD158 antigen-like family member A
  • p58 killer cell inhibitory receptor KIR-K64
  • killer inhibitory receptor 2-2-1
  • p58 NK receptor CL-42/47.11
  • KIR2DL protein
  • p58 natural killer cell receptor clones CL-42/47.11
  • KIR2DL1
  • killer cell immunoglobulin-like receptor 2DL1
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
  • natural killer-associated transcript 1
  • NKAT-1
  • p58.1 MHC class-I-specific NK receptor
In more languages

Statements

molecular function
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells
GOA
curator
UniProt
UniProt protein ID
P43626
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43626
determination method
IPI
retrieved
8 April 2019
stated in
Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43626
determination method
IPI
retrieved
8 April 2019
stated in
Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43626
determination method
IPI
retrieved
8 April 2019
stated in
KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43626
determination method
IPI
retrieved
8 April 2019
stated in
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43626
determination method
IPI
cell component

Identifiers

MeSH descriptor ID
D054342
subject named as
Receptors, KIR2DL1
0 references
Ensembl protein ID
 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21119880&oldid=2022981812"