(Q21120105)

http://www.ebi.ac.uk/interpro/protein/P19404

Thioredoxin-like superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19404

1 reference

13 November 2019

1 reference

13 November 2019

NADH dehydrogenase activity

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

electron transfer activity

1 reference

8 April 2019

Structural organization and chromosomal localization of the human nuclear gene (NDUFV2) for the 24-kDa iron-sulfur subunit of complex I in mitochondrial respiratory chain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

NADH dehydrogenase (ubiquinone) activity

NAS

4 references

27 March 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

27 March 2018

Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

27 March 2018

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

iron-sulfur cluster binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

2 iron, 2 sulfur cluster binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

1 reference

8 April 2019

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

NADH dehydrogenase (ubiquinone) activity

IPI

5 references

10 September 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

10 September 2018

Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

10 September 2018

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

NADH dehydrogenase (ubiquinone) activity

3 references

8 April 2019

Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

mitochondrial respiratory chain complex I

3 references

27 March 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

27 March 2018

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

27 March 2018

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

plasma membrane respiratory chain complex I

IDA

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

mitochondrial respiratory chain complex I

4 references

8 April 2019

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

nervous system development

biological process

1 reference

8 April 2019

Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

cardiac muscle tissue development

IMP

1 reference

8 April 2019

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

mitochondrial respiratory chain complex I assembly

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

mitochondrial electron transport, NADH to ubiquinone

TAS

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

27 March 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

27 March 2018

Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

27 March 2018

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

mitochondrial electron transport, NADH to ubiquinone

IMP

4 references

10 September 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

10 September 2018

Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

10 September 2018

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19404&geneProductId=UniProtKB:P19404

mitochondrial electron transport, NADH to ubiquinone

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19404

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1431

metformin hydrochloride

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023