(Q21122435)

http://www.ebi.ac.uk/interpro/protein/O43614

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

peptide hormone binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

G protein-coupled receptor activity

signal transducer activity

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

neuropeptide receptor activity

1 reference

8 April 2019

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

TAS

orexin receptor activity

3 references

5 June 2018

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

5 June 2018

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

G protein-coupled receptor activity

IDA

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

orexin receptor activity

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

integral component of plasma membrane

integral component of plasma membrane

IDA

TAS

3 references

8 April 2019

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

phospholipase C-activating G protein-coupled receptor signaling pathway

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

cellular response to hormone stimulus

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

regulation of circadian sleep/wake cycle, sleep

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

circadian sleep/wake cycle process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

chemical synaptic transmission

1 reference

8 April 2019

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

regulation of cytosolic calcium ion concentration

TAS

1 reference

8 April 2019

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

regulation of circadian sleep/wake cycle, wakefulness

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

neuropeptide signaling pathway

ISS

3 references

8 April 2019

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

4 references

8 April 2019

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

G protein-coupled receptor signaling pathway

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43614&geneProductId=UniProtKB:O43614

G protein-coupled receptor signaling pathway

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43614

physically interacts with

1 reference

2886

17 August 2016

1 reference

4037

17 August 2016

1 reference

4460

17 August 2016

1 reference

1703

17 August 2016

1 reference

4461

17 August 2016

1 reference

2890

17 August 2016

1 reference

4038

17 August 2016

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL4650216

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2107822

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3545367

has part(s)

GPCR, rhodopsin-like, 7TM

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O43614

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

4 August 2016