(Q21123025)

English

UL16 binding protein 3

mammalian protein found in Homo sapiens

ULBP3
NKG2D ligand 3
UL16-binding protein 3
retinoic acid early transcript 1N
ALCAN-gamma

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Statements

1 reference

13 November 2019

MHC classes I/II-like antigen recognition protein

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BZM4

MHC class I-like antigen recognition-like superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BZM4

MHC class I-like antigen recognition-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

natural killer cell lectin-like receptor binding

1 reference

24 April 2018

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZM4&geneProductId=UniProtKB:Q9BZM4

3 references

8 April 2019

A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

8 April 2019

Four novel ULBP splice variants are ligands for human NKG2D.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

8 April 2019

Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

IPI

natural killer cell lectin-like receptor binding

anchored component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

IEA

anchored component of plasma membrane

1 reference

8 April 2019

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

IBA

external side of plasma membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

IBA

biological process

natural killer cell activation

1 reference

24 April 2018

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZM4&geneProductId=UniProtKB:Q9BZM4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

IEA

natural killer cell mediated cytotoxicity

1 reference

24 April 2018

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZM4&geneProductId=UniProtKB:Q9BZM4

determination method

IDA

regulation of immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

TAS

immune system process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

IEA

T cell mediated cytotoxicity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

IBA

natural killer cell activation

determination method

IBA

IDA

natural killer cell mediated cytotoxicity

determination method

IBA

IDA

susceptibility to natural killer cell mediated cytotoxicity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZM4

determination method

IBA

has part(s)

MHC class I-like antigen recognition-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BZM4

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

9 August 2016

language of work or name

English

(Q21123025)

UL16 binding protein 3

Statements

Identifiers

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