(Q21123743)

serine/threonine-protein kinase pim-1/2/3

1 reference

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

protein serine/threonine kinase activity

IEA

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86V86&geneProductId=UniProtKB:Q86V86

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86V86&geneProductId=UniProtKB:Q86V86

27 March 2018

Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86V86&geneProductId=UniProtKB:Q86V86

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

IDA

protein kinase activity

1 reference

8 April 2019

1 reference

8 April 2019

Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

2 references

protein serine/threonine kinase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

8 April 2019

Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

protein autophosphorylation

IDA

biological process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

regulation of mitotic cell cycle

IEA

1 reference

27 March 2018

Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86V86&geneProductId=UniProtKB:Q86V86

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

regulation of mitotic cell cycle

IEA

negative regulation of apoptotic process

IBA

IMP

3 references

8 April 2019

Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86V86

physically interacts with

IBA

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1952329

has part(s)

serine/threonine-protein kinase, active site

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference