(Q21124058)

Immunoglobulin-like fold

1 reference

Rel homology domain (RHD), DNA-binding domain superfamily

1 reference

Nuclear factor of activated T-cells 1

1 reference

Immunoglobulin E-set

1 reference

IPT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rel homology dimerisation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rel homology domain (RHD), DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

DNA-binding transcription factor activity

Solution structure of the core NFATC1/DNA complex

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

24 April 2018

Divergent hTAFII31-binding motifs hidden in activation domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

24 April 2018

mitogen-activated protein kinase p38 binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

FK506 binding

1 reference

8 April 2019

Characterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

protein binding

6 references

8 April 2019

NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer Proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

The LxVP and PxIxIT NFAT motifs bind jointly to overlapping epitopes on calcineurin's catalytic domain distant to the regulatory domain.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

3 references

10 September 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

NAS

10 September 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

Norwegian University of Science and Technology, Systems Biology team

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

RNA polymerase II cis-regulatory region sequence-specific DNA binding

ISA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

chromatin binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

DNA-binding transcription factor activity

Solution structure of the core NFATC1/DNA complex

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Divergent hTAFII31-binding motifs hidden in activation domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

transcription factor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

4 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

ISA

cell component

cytoplasm

NF-AT components define a family of transcription factors targeted in T-cell activation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

1 reference

24 April 2018

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

3 references

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

24 April 2018

Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

nuclear body

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

transcription regulator complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

intracellular signal transduction

biological process

1 reference

8 April 2019

Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

1 reference

8 April 2019

calcineurin-NFAT signaling cascade

1 reference

24 April 2018

Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

transcription by RNA polymerase II

1 reference

8 April 2019

Characterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

1 reference

24 April 2018

positive regulation of transcription, DNA-templated

2 references

8 April 2019

Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

Fc-epsilon receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

1 reference

8 April 2019

positive regulation of transcription by RNA polymerase II

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

24 April 2018

Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

24 April 2018

Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95644&geneProductId=UniProtKB:O95644

Wnt signaling pathway, calcium modulating pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

1 reference

8 April 2019

negative regulation of Wnt signaling pathway

Parkinsons Disease Gene Ontology Initiative

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

negative regulation of vascular associated smooth muscle cell differentiation

1 reference

8 April 2019

MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

cytokine production

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

calcineurin-NFAT signaling cascade

Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

positive regulation of transcription by RNA polymerase II

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

aortic valve morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

pulmonary valve morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95644

1 reference

Rel homology dimerisation domain

1 reference

Rel homology domain (RHD), DNA-binding domain

1 reference